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Lidocaine Hydrochloride hydrate
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Catalog No. T1144LCas No. 6108-05-0
Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.
Lidocaine Hydrochloride hydrate
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Purity: 99.95%
Catalog No. T1144LCas No. 6108-05-0
Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 mg | $30 | In Stock | In Stock | |
| 100 mg | $42 | In Stock | In Stock | |
| 500 mg | $96 | In Stock | In Stock | |
| 1 g | $142 | In Stock | In Stock | |
| 2 g | $198 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $29 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.95%
Color:White
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Product Introduction
Lidocaine Hydrochloride hydrate AI Summary
Lidocaine Hydrochloride hydrate shows bioactivity in multiple assays, exhibiting potencies of 920.0 nM in a qHTS assay for Lipid Storage Modulators in Drosophila S3 Cells, 29092.9 nM in an Nrf2 qHTS screen for inhibitors, and 89125.1 nM in an HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. It is involved in drug metabolism, particularly N-deethylation, in human liver microsomes as well as in the activity of rat recombinant CYP1A2. The compound shows diverse Vmax and Km values, which indicate its ability to interact with enzymes and undergo metabolic processing. It demonstrates stability based on HPLC retention times and has been assessed for both hepatic and intrinsic clearance in healthy humans. Additionally, Lidocaine Hydrochloride hydrate exhibits good binding affinity and fraction unbound properties in human liver microsomes and rat CYP1A2..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property. |
| Molecular Weight | 288.82 |
| Formula | C14H22N2O·HCl·H2O |
| Cas No. | 6108-05-0 |
| Smiles | c1(NC(=O)CN(CC)CC)c(cccc1C)C.Cl.O |
| Relative Density. | no data available |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 25 mg/mL (86.56 mM), Sonication is recommended.  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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