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D-(+)-Glucono-1,5-lactone

🥰Excellent
Catalog No. T0933Cas No. 90-80-2
Alias Gluconolactone, Gluconic acid lactone, Delta-Gluconolactone

D-(+)-Glucono-1,5-lactone (Gluconolactone) is a naturally occurring food additive used as a sequestrant, acidifier, curing agent, pickling agent, or leavening agent. It is a cyclic ester of D-gluconic acid and appears as a white, odorless crystalline powder.

D-(+)-Glucono-1,5-lactone

D-(+)-Glucono-1,5-lactone

🥰Excellent
Purity: 99.64%
Catalog No. T0933Alias Gluconolactone, Gluconic acid lactone, Delta-GluconolactoneCas No. 90-80-2
D-(+)-Glucono-1,5-lactone (Gluconolactone) is a naturally occurring food additive used as a sequestrant, acidifier, curing agent, pickling agent, or leavening agent. It is a cyclic ester of D-gluconic acid and appears as a white, odorless crystalline powder.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 g$31-In Stock
25 g$48-In Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.64%
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Product Introduction

Bioactivity
Description
D-(+)-Glucono-1,5-lactone (Gluconolactone) is a naturally occurring food additive used as a sequestrant, acidifier, curing agent, pickling agent, or leavening agent. It is a cyclic ester of D-gluconic acid and appears as a white, odorless crystalline powder.
SynonymsGluconolactone, Gluconic acid lactone, Delta-Gluconolactone
Chemical Properties
Molecular Weight178.14
FormulaC6H10O6
Cas No.90-80-2
SmilesC(O)[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)C(=O)O1
Relative Density.1.72 g/cm3. Temperature:20 °C.
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (280.68 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (11.23 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.6136 mL28.0678 mL56.1356 mL280.6781 mL
5 mM1.1227 mL5.6136 mL11.2271 mL56.1356 mL
10 mM0.5614 mL2.8068 mL5.6136 mL28.0678 mL
20 mM0.2807 mL1.4034 mL2.8068 mL14.0339 mL
50 mM0.1123 mL0.5614 mL1.1227 mL5.6136 mL
100 mM0.0561 mL0.2807 mL0.5614 mL2.8068 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Δ-GluconolactoneReactiveOxygenSpeciesReactive Oxygen SpeciesLPHInhibitorinhibitEndogenousMetaboliteEndogenous MetaboliteD-Glucono-1,5-lactoneD(+)Glucono1,5lactoneD (+) Glucono 1,5 lactone
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