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Flutriafol

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Catalog No. T7867Cas No. 76674-21-0

Flutriafol is a pesticide, demethylation inhibitor, and NMDA receptor agonist

Flutriafol

Flutriafol

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🥰Excellent
Purity: 98.75%
Catalog No. T7867Cas No. 76674-21-0
Flutriafol is a pesticide, demethylation inhibitor, and NMDA receptor agonist
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$39In StockIn Stock
50 mg$55In StockIn Stock
100 mg$76In StockIn Stock
200 mg$98In StockIn Stock
500 mg$187In StockIn Stock
1 g$276In StockIn Stock
1 mL x 10 mM (in DMSO)$39In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:98.75%
Appearance:Solid
Color:White
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Product Introduction

Flutriafol AI Summary
Flutriafol shows bioactivity as a small molecule activator of the rat pregnane X receptor (rPXR) signaling pathway with a potency of 28183.8 nM. It also exhibits significant fungicidal properties, demonstrating mycelial growth inhibition against Macrophomina phaseolina with an ED50 of 13.1 mg/kg at 27°C over 5 days and a 50.0% reduction in disease incidence in non-grafted melon plants when applied as a soil drench at 250 ml/1000 m² three times during the growing season. Additionally, Flutriafol shows antifungal activity against Leptosphaeria maculans with an ED50 of 0.45 µg/ml..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Flutriafol is a pesticide, demethylation inhibitor, and NMDA receptor agonist
Chemical Properties
Molecular Weight301.29
FormulaC16H13F2N3O
Cas No.76674-21-0
SmilesOC(CN1C=NC=N1)(C1=CC=C(F)C=C1)C1=CC=CC=C1F
Relative Density.1.29 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 22.5 mg/mL (74.68 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3191 mL16.5953 mL33.1906 mL165.9531 mL
5 mM0.6638 mL3.3191 mL6.6381 mL33.1906 mL
10 mM0.3319 mL1.6595 mL3.3191 mL16.5953 mL
20 mM0.1660 mL0.8298 mL1.6595 mL8.2977 mL
50 mM0.0664 mL0.3319 mL0.6638 mL3.3191 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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