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3-O-Methylgalangin

Name: 3-O-Methylgalangin
Brand: TargetMol
SKU: T5707
Price: 85 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T5707Cas No. 6665-74-3

Alias GALANGIN-3-METHYLETHER, 3-Methylgalangin

3-O-Methylgalangin (GALANGIN-3-METHYLETHER) has antibacterial activity, it has inhibitory effects on Pseudomonas aeruginosa. GALANGIN-3-METHYLETHER has hypolipidemic activity, the action is due to the inhibition of pancreatic lipase.

3-O-Methylgalangin

🥰Excellent

Purity: 98.21%

Catalog No. T5707Alias GALANGIN-3-METHYLETHER, 3-MethylgalanginCas No. 6665-74-3

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$85	In Stock	In Stock
5 mg	$172	In Stock	In Stock
10 mg	$277	In Stock	In Stock
25 mg	$469	In Stock	In Stock
50 mg	$673	In Stock	In Stock
100 mg	$939	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$163	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.21%

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	3-O-Methylgalangin (GALANGIN-3-METHYLETHER) has antibacterial activity, it has inhibitory effects on Pseudomonas aeruginosa. GALANGIN-3-METHYLETHER has hypolipidemic activity, the action is due to the inhibition of pancreatic lipase.
In vitro	GALANGIN-3-METHYLETHER markedly reduced the viability of Leishmania amastigotes.
Cell Research	L. amazonensis amastigotes were maintained and cultured axenically .Washed parasites were resuspended in RPMI-1640 medium supplemented with 4% fetal calf serum, pH 5.0, and incubated at 33 C for 18 h with crude extracts (1 mg/mL) or isolated compounds(GALANGIN-3-METHYLETHER) (0.014, 0.084, 0.5, and 1.0 mg/mL) dissolved in dimethyl sulfoxide (DMSO)/RPMI-1640 (1:99).?The amastigote viability was assessed colorimetrically by the reduction of a tetrazolium salt (MTT) as.?Absorbances were expressed as percentages relative to untreated controls.?Amphotericin B (0.02 mg/mL) was used as the positive control and DMSO/RPMI-1640 (1:99) as negative control.?The bioassays were carried out in triplicate.
Synonyms	GALANGIN-3-METHYLETHER, 3-Methylgalangin

Chemical Properties

Molecular Weight	284.26
Formula	C₁₆H₁₂O₅
Cas No.	6665-74-3
Smiles	COc1c(oc2cc(O)cc(O)c2c1=O)-c1ccccc1
Relative Density.	1.47g/cm3

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 25 mg/mL (87.95 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 1 mg/mL (3.52 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5179 mL	17.5895 mL	35.1791 mL	175.8953 mL
5 mM	0.7036 mL	3.5179 mL	7.0358 mL	35.1791 mL
10 mM	0.3518 mL	1.7590 mL	3.5179 mL	17.5895 mL
20 mM	0.1759 mL	0.8795 mL	1.7590 mL	8.7948 mL
50 mM	0.0704 mL	0.3518 mL	0.7036 mL	3.5179 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc