Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases.[1] At 10 µM, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its active form, caspase cascade activation, and apoptosis.[2]
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 170.00 | |
1 mg | 35 days | $ 325.00 | |
5 mg | 35 days | $ 1,420.00 |
Description | Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases.[1] At 10 µM, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its active form, caspase cascade activation, and apoptosis.[2] |
Synonyms | Z-AEVD-FMK, Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone |
Molecular Weight | 610.63 |
Formula | C28H39FN4O10 |
CAS No. | 1135688-47-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL
You can also refer to dose conversion for different animals. More
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Z-AEVD-FMK 1135688-47-9 Z AEVD FMK Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone ZAEVDFMK inhibitor inhibit