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Nisoxetine hydrochloride

Name: Nisoxetine hydrochloride
Brand: TargetMol
SKU: T23070
Price: 64 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T23070Cas No. 57754-86-6

Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor

Nisoxetine hydrochloride

🥰Excellent

Purity: 99.21%

Catalog No. T23070Cas No. 57754-86-6

Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$64	In Stock	In Stock
10 mg	$97	In Stock	In Stock
25 mg	$178	In Stock	In Stock
50 mg	$288	In Stock	In Stock
100 mg	$457	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.21%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor
Targets&IC50	NET:Kd: 0.76 nM

Chemical Properties

Molecular Weight	307.82
Formula	C₁₇H₂₁NO₂·HCl
Cas No.	57754-86-6
Smiles	Cl.CNCCC(Oc1ccccc1OC)c1ccccc1
Relative Density.	1.054g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (146.19 mM), Sonication is recommended.

H2O: < 30.78 mg/mL, Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2487 mL	16.2433 mL	32.4865 mL	162.4326 mL
5 mM	0.6497 mL	3.2487 mL	6.4973 mL	32.4865 mL
10 mM	0.3249 mL	1.6243 mL	3.2487 mL	16.2433 mL
20 mM	0.1624 mL	0.8122 mL	1.6243 mL	8.1216 mL
50 mM	0.0650 mL	0.3249 mL	0.6497 mL	3.2487 mL
100 mM	0.0325 mL	0.1624 mL	0.3249 mL	1.6243 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc