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Hexacyclen

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Catalog No. T84874Cas No. 296-35-5
Alias Hexaaza-18-crown-6, 1,4,7,10,13,16-Hexazacyclooctadecane

Hexacyclen is an analogue of 18-crown-6, exhibiting antagonistic and blocking effects on the extracellular calcium-sensing receptor with an EC50 of 20 μM. Possessing multiple secondary amine groups, Hexacyclen serves as an excellent electron donor and functions as a block copolymer.

Hexacyclen
Other Forms of Hexacyclen:

Hexacyclen

🥰Excellent
Catalog No. T84874Alias Hexaaza-18-crown-6, 1,4,7,10,13,16-HexazacyclooctadecaneCas No. 296-35-5
Hexacyclen is an analogue of 18-crown-6, exhibiting antagonistic and blocking effects on the extracellular calcium-sensing receptor with an EC50 of 20 μM. Possessing multiple secondary amine groups, Hexacyclen serves as an excellent electron donor and functions as a block copolymer.
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10 mg$29In Stock
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Product Introduction

Bioactivity
Description
Hexacyclen is an analogue of 18-crown-6, exhibiting antagonistic and blocking effects on the extracellular calcium-sensing receptor with an EC50 of 20 μM. Possessing multiple secondary amine groups, Hexacyclen serves as an excellent electron donor and functions as a block copolymer.
In vitro
Hexacyclen is a biochemical reagent with application value in the fields of biomaterials or organic compound research, suitable for life science-related studies.
SynonymsHexaaza-18-crown-6, 1,4,7,10,13,16-Hexazacyclooctadecane
Chemical Properties
Molecular Weight258.41
FormulaC12H30N6
Cas No.296-35-5
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
H2O: 80.00 mg/mL (309.59 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM3.8698 mL19.3491 mL38.6982 mL193.4910 mL
5 mM0.7740 mL3.8698 mL7.7396 mL38.6982 mL
10 mM0.3870 mL1.9349 mL3.8698 mL19.3491 mL
20 mM0.1935 mL0.9675 mL1.9349 mL9.6745 mL
50 mM0.0774 mL0.3870 mL0.7740 mL3.8698 mL
100 mM0.0387 mL0.1935 mL0.3870 mL1.9349 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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