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SJB2-043

🥰Excellent
Catalog No. T7678Cas No. 63388-44-3

SJB2-043, an inhibitor of USP1-UAF1, has an IC50 of 544 nM.

SJB2-043

SJB2-043

🥰Excellent
Purity: 98.44%
Catalog No. T7678Cas No. 63388-44-3
SJB2-043, an inhibitor of USP1-UAF1, has an IC50 of 544 nM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$47In StockIn Stock
10 mg$80In StockIn Stock
25 mg$178In StockIn Stock
50 mg$289In StockIn Stock
100 mg$455In StockIn Stock
200 mg$657-In Stock
1 mL x 10 mM (in DMSO)$52In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.44%
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Product Introduction

Bioactivity
Description
SJB2-043, an inhibitor of USP1-UAF1, has an IC50 of 544 nM.
Targets&IC50
USP1/UAF1:544 nM
Chemical Properties
Molecular Weight275.26
FormulaC17H9NO3
Cas No.63388-44-3
SmilesO=C1c2nc(oc2C(=O)c2ccccc12)-c1ccccc1
Relative Density.1.373 g/cm3 (Predicted)
ColorYellow
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 3.33 mg/mL (12.1 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.6329 mL18.1646 mL36.3293 mL181.6464 mL
5 mM0.7266 mL3.6329 mL7.2659 mL36.3293 mL
10 mM0.3633 mL1.8165 mL3.6329 mL18.1646 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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