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Mogroside IIe

Name: Mogroside IIe
Brand: TargetMol
SKU: TN1056
Price: 53 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1056Cas No. 88901-38-6

Mogroside IIe is a major bioactive component of unripe S. grosvenorii fruit that downregulates the IL-9/IL-9 receptor pathway.

Mogroside IIe

🥰Excellent

Purity: 99.93%

Catalog No. TN1056Cas No. 88901-38-6

Mogroside IIe is a major bioactive component of unripe S. grosvenorii fruit that downregulates the IL-9/IL-9 receptor pathway.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$53	In Stock	In Stock
5 mg	$131	In Stock	In Stock
10 mg	$193	In Stock	In Stock
25 mg	$313	In Stock	In Stock
50 mg	$453	In Stock	In Stock
100 mg	$636	In Stock	In Stock
200 mg	$857	-	In Stock
1 mL x 10 mM (in DMSO)	$203	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.93%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Mogroside IIe is a major bioactive component of unripe S. grosvenorii fruit that downregulates the IL-9/IL-9 receptor pathway.
In vitro	Mogroside IIE decreased the activity of trypsin and cathepsin B induced by cerulein plus lipopolysaccharide (LPS) in the pancreatic acinar cell line AR42J and primary acinar cells in a dose- and time-dependent manner[1].
In vivo	Mogroside IIE treatment decreased the levels of serum lipase and serum amylase in mice injected with cerulein plus LPS without influencing inflammation significantly. A multi-cytokine array revealed that mogroside IIE decreased the level of interleukin 9 (IL-9) in AP mice[1].

Chemical Properties

Molecular Weight	801.01
Formula	C₄₂H₇₂O₁₄
Cas No.	88901-38-6
Smiles	[H][C@@]1(CC[C@@]2(C)[C@]3([H])CC=C4[C@@]([H])(CC[C@H](O[C@]5([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C4(C)C)[C@]3(C)[C@H](O)C[C@]12C)[C@H](C)CC[C@@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C(C)(C)O
Relative Density.	1.33 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (124.84 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (4.99 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2484 mL	6.2421 mL	12.4842 mL	62.4212 mL
5 mM	0.2497 mL	1.2484 mL	2.4968 mL	12.4842 mL
10 mM	0.1248 mL	0.6242 mL	1.2484 mL	6.2421 mL
20 mM	0.0624 mL	0.3121 mL	0.6242 mL	3.1211 mL
50 mM	0.0250 mL	0.1248 mL	0.2497 mL	1.2484 mL
100 mM	0.0125 mL	0.0624 mL	0.1248 mL	0.6242 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc