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Efegatran sulfate

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Catalog No. T25364LCas No. 126721-07-1
Alias LY-294468 sulfate, LY294468 sulfate, LY 294468 sulfate, GYKI-14766 sulfate

Efegatran sulfate (LY294468 sulfate) is a potent thrombin inhibitor used in the treatment of thrombotic disorders.

Efegatran sulfate

Efegatran sulfate

Copy Product Info
🥰Excellent
Catalog No. T25364LAlias LY-294468 sulfate, LY294468 sulfate, LY 294468 sulfate, GYKI-14766 sulfateCas No. 126721-07-1
Efegatran sulfate (LY294468 sulfate) is a potent thrombin inhibitor used in the treatment of thrombotic disorders.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$323In StockIn Stock
5 mg$720In StockIn Stock
10 mg$953In StockIn Stock
25 mg$1,430In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:≥98%
ee:100%
Appearance:Solid
Color:White
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Product Introduction

Efegatran sulfate AI Summary
Efegatran sulfate exhibits dose-dependent anticoagulant activity, with a notable anticoagulant efficiency rated at greater than 0.63 mg/kg/hr..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Efegatran sulfate (LY294468 sulfate) is a potent thrombin inhibitor used in the treatment of thrombotic disorders.
SynonymsLY-294468 sulfate, LY294468 sulfate, LY 294468 sulfate, GYKI-14766 sulfate
Chemical Properties
Molecular Weight514.6
FormulaC21H34N6O7S
Cas No.126721-07-1
SmilesS(=O)(=O)(O)O.C([C@@H](CC1=CC=CC=C1)NC)(=O)N2[C@H](C(N[C@@H](CCCNC(=N)N)C=O)=O)CCC2
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 2.57 mg/mL (4.99 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9433 mL9.7163 mL19.4326 mL97.1628 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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