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Miglustat

Name: Miglustat
Brand: TargetMol
SKU: T12039
Price: 38 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T12039Cas No. 72599-27-0

Alias OGT918, N-Butyldeoxynojirimycin, NB-DNJ

Miglustat (NB-DNJ) is an alkylated product of imino sugar deoxynojirimycin.It is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1).

Miglustat

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Purity: 99.92%

Catalog No. T12039Alias OGT918, N-Butyldeoxynojirimycin, NB-DNJCas No. 72599-27-0

Miglustat (NB-DNJ) is an alkylated product of imino sugar deoxynojirimycin.It is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1).

Pack Size	Price	Availability
1 mg	$38	In Stock
5 mg	$89	In Stock
10 mg	$139	In Stock
25 mg	$258	In Stock
50 mg	$428	In Stock
100 mg	$623	In Stock
1 mL x 10 mM (in DMSO)	$98	In Stock

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Batch Information

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Purity:99.92%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Miglustat (NB-DNJ) is an alkylated product of imino sugar deoxynojirimycin.It is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1).
Synonyms	OGT918, N-Butyldeoxynojirimycin, NB-DNJ

Chemical Properties

Molecular Weight	219.28
Formula	C₁₀H₂₁NO₄
Cas No.	72599-27-0
Smiles	CCCCN1C[C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O
Relative Density.	1.234 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 25 mg/mL (114.01 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.5604 mL	22.8019 mL	45.6038 mL	228.0190 mL
5 mM	0.9121 mL	4.5604 mL	9.1208 mL	45.6038 mL
10 mM	0.4560 mL	2.2802 mL	4.5604 mL	22.8019 mL
20 mM	0.2280 mL	1.1401 mL	2.2802 mL	11.4009 mL
50 mM	0.0912 mL	0.4560 mL	0.9121 mL	4.5604 mL
100 mM	0.0456 mL	0.2280 mL	0.4560 mL	2.2802 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc