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Butylhydroxyanisole (Synonyms: E320, Butylated hydroxyanisole, BHA)

Name: Butylhydroxyanisole
Brand: TargetMol
SKU: T0787
Price: 42 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T0787 Copy Product Info

Purity: 99.63%

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Butylhydroxyanisole (BHA) is an antioxidant consisting of a mixture of two isomeric organic compounds, 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.

Butylhydroxyanisole

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Catalog No. T0787

Synonyms E320, Butylated hydroxyanisole, BHA

Butylhydroxyanisole (BHA) is an antioxidant consisting of a mixture of two isomeric organic compounds, 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.

Cas No. 25013-16-5

Pack Size	Price	USA Stock	Global Stock
500 mg	$42	In Stock	In Stock
1 g	$50	-	In Stock
1 mL x 10 mM (in DMSO)	$46	In Stock	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.63%

Appearance:Solid

Color:White to Red

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COA GC HNMR LCMS

Product Introduction

Butylhydroxyanisole AI Summary

Butylhydroxyanisole exhibits a range of significant bioactivities, notably its strong antioxidant properties. It shows potent activity in scavenging various free radicals, including DPPH, with IC50 values ranging between 4.5 µg/mL and 14100000.0 nM, and superoxide anion radicals with an IC50 value of 966000.0 nM. Additionally, it demonstrates antioxidant capabilities through ABTS radical scavenging (IC50 of 10710.0 nM) and effective inhibition of lipid peroxidation (inhibition rate of 91.0% at 1.80 µg/mL). The compound also possesses antibacterial activity, significantly against Propionibacterium acnes, and displays antifungal activity against Saccharomyces cerevisiae and Pityrosporum ovale. Furthermore, it has been observed to modulate caspase-mediated apoptosis in mouse L1210 cells and induce DNA fragmentation in human HL60 cells. Overall, Butylhydroxyanisole shows promise as a multi-functional agent with potential applications in antioxidant, antibacterial, antifungal, and anticancer therapies..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Butylhydroxyanisole (BHA) is an antioxidant consisting of a mixture of two isomeric organic compounds, 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.
Synonyms	E320, Butylated hydroxyanisole, BHA

Chemical Properties

Molecular Weight	180.25
Formula	C₁₁H₁₆O₂
Cas No.	25013-16-5
Smiles	COc1ccc(O)c(c1)C(C)(C)C
Relative Density.	0.69 g/cm3. Temperature:28.6 °C.;0.69 g/cm3. Temperature:28.6 °C.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (332.87 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.5479 mL	27.7393 mL	55.4785 mL	277.3925 mL
5 mM	1.1096 mL	5.5479 mL	11.0957 mL	55.4785 mL
10 mM	0.5548 mL	2.7739 mL	5.5479 mL	27.7393 mL
20 mM	0.2774 mL	1.3870 mL	2.7739 mL	13.8696 mL
50 mM	0.1110 mL	0.5548 mL	1.1096 mL	5.5479 mL
100 mM	0.0555 mL	0.2774 mL	0.5548 mL	2.7739 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc