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5-Amino-3H-imidazole-4-Carboxamide

🥰Excellent
Catalog No. T1705Cas No. 360-97-4
Alias AICA, 5-Aminoimidazole-4-carboxamide, 4-Amino-5-imidazolecarboxamide

5-Amino-3H-imidazole-4-Carboxamide (AICA) is an imidazole derivative and a metabolite of the antineoplastic agents BIC and DIC. It serves as a condensation agent in the preparation of nucleosides and nucleotides, and when compounded with orotic acid, it is used to treat liver diseases.

5-Amino-3H-imidazole-4-Carboxamide

5-Amino-3H-imidazole-4-Carboxamide

🥰Excellent
Purity: 99.20%
Catalog No. T1705Alias AICA, 5-Aminoimidazole-4-carboxamide, 4-Amino-5-imidazolecarboxamideCas No. 360-97-4
5-Amino-3H-imidazole-4-Carboxamide (AICA) is an imidazole derivative and a metabolite of the antineoplastic agents BIC and DIC. It serves as a condensation agent in the preparation of nucleosides and nucleotides, and when compounded with orotic acid, it is used to treat liver diseases.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 g$29-In Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.20%
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Product Introduction

Bioactivity
Description
5-Amino-3H-imidazole-4-Carboxamide (AICA) is an imidazole derivative and a metabolite of the antineoplastic agents BIC and DIC. It serves as a condensation agent in the preparation of nucleosides and nucleotides, and when compounded with orotic acid, it is used to treat liver diseases.
SynonymsAICA, 5-Aminoimidazole-4-carboxamide, 4-Amino-5-imidazolecarboxamide
Chemical Properties
Molecular Weight126.12
FormulaC4H6N4O
Cas No.360-97-4
SmilesNC(=O)C1=C(N)NC=N1
Relative Density.1.3659 g/cm3 (Estimated)
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (792.90 mM), Sonication is recommended.
H2O: 20 mg/mL (158.58 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM7.9290 mL39.6448 mL79.2896 mL396.4478 mL
5 mM1.5858 mL7.9290 mL15.8579 mL79.2896 mL
10 mM0.7929 mL3.9645 mL7.9290 mL39.6448 mL
20 mM0.3964 mL1.9822 mL3.9645 mL19.8224 mL
50 mM0.1586 mL0.7929 mL1.5858 mL7.9290 mL
100 mM0.0793 mL0.3964 mL0.7929 mL3.9645 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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2 Enter the in vivo formulation:
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Keywords

InhibitorinhibitEndogenousMetaboliteEndogenous Metabolite5-Amino-3H-imidazole-4-Carboxamide5Amino3Himidazole4Carboxamide5 Amino 3H imidazole 4 Carboxamide
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