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Dynamin IN-2

Catalog No. T64369

Dynamin IN-2 (compound 43) is a Wiskostatin analogue. Dynamin IN-2 is a potent dynamin inhibitor (dynamin I GTPase, IC50= 1.0 μM). Dynamin IN-2 blocks clathrin mediated endocytosis (CME) (IC50= 9.5 μM).

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Dynamin IN-2, CAS N/A
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Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Dynamin IN-2 (compound 43) is a Wiskostatin analogue. Dynamin IN-2 is a potent dynamin inhibitor (dynamin I GTPase, IC50= 1.0 μM). Dynamin IN-2 blocks clathrin mediated endocytosis (CME) (IC50= 9.5 μM).
Molecular Weight N/A

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Cossar PJ, et al. Wiskostatin and other carbazole scaffolds as off target inhibitors of dynamin I GTPase activity and endocytosis. Eur J Med Chem. 2022 Dec 15;247:115001.

Related Products

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Dynamin inhibitory peptide, myristoylated acetate Hydroxy-Dynasore Dynamin IN-2 Schaftoside Dynapyrazole A Tetradecyltrimethylammonium bromide Trimethyloctadecylammonium bromide Mdivi-1

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Dynamin IN-2 Cytoskeletal Signaling Dynamin Inhibitor inhibitor inhibit