Shopping Cart

Your shopping cart is currently empty

Sodium Thiocyanate

Name: Sodium Thiocyanate
Brand: TargetMol
SKU: T8033
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T8033Cas No. 540-72-7

Sodium Thiocyanate, one of the main sources of the thiocyanate anion, is used as a precursor for the synthesis of pharmaceuticals and other specialty chemicals.

Sodium Thiocyanate

Copy Product Info

😃Good

Catalog No. T8033Cas No. 540-72-7

Sodium Thiocyanate, one of the main sources of the thiocyanate anion, is used as a precursor for the synthesis of pharmaceuticals and other specialty chemicals.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
10 g	$29	-	In Stock
1 mL x 10 mM (in DMSO)	$29	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Appearance:Solid

Color:White

Resource Download

COA

Product Introduction

Sodium Thiocyanate AI Summary

Sodium Thiocyanate exhibits broad inhibitory activity against a variety of carbonic anhydrase (CA) enzymes across different species. It has demonstrated inhibitory effects on human CA1 and CA2, with Ki values of 200,000 nM and 1,600,000 nM, respectively, as well as on CA enzymes from Streptococcus pneumoniae (Ki = 380,000 nM), Dicentrarchus labrax, Leptonychotes weddellii, and Astrosclera willeyana. The compound shows potent inhibition on Porphyromonas gingivalis gamma-carbonic anhydrase (Ki = 93,000 nM) and also affects CA enzymes from Methanosarcina thermophila (Ki = 7,000,000 nM), Nostoc commune (Ki = 8,100,000 nM), and Pseudoalteromonas haloplanktis (Ki = 9,300,000 nM). Analysis through multiple assays, such as the stopped-flow CO2 hydration method, reveals a wide range of Ki values, indicating variable potency across different CA isoforms and species. Notably, Sodium Thiocyanate also inhibits His6-tagged Mycobacterium tuberculosis Rv3588c, with a Ki value of 8,000 nM, as well as Pseudomonas aeruginosa PAO1 type-2 beta-CA psCA3 (Ki = 610,000 nM). These findings suggest Sodium Thiocyanate's potential utility as a multi-target CA inhibitor across diverse biological contexts..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

Sodium Thiocyanate, one of the main sources of the thiocyanate anion, is used as a precursor for the synthesis of pharmaceuticals and other specialty chemicals.

Chemical Properties

Molecular Weight	81.07
Formula	CNNaS
Cas No.	540-72-7
Smiles	N#C[S-].[Na+]
Relative Density.	1.76 g/cm3. Temperature:20 °C.;1.76. Temperature:20 °C.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (616.75 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (24.67 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	12.3350 mL	61.6751 mL	123.3502 mL	616.7510 mL
5 mM	2.4670 mL	12.3350 mL	24.6700 mL	123.3502 mL
10 mM	1.2335 mL	6.1675 mL	12.3350 mL	61.6751 mL
20 mM	0.6168 mL	3.0838 mL	6.1675 mL	30.8375 mL
50 mM	0.2467 mL	1.2335 mL	2.4670 mL	12.3350 mL
100 mM	0.1234 mL	0.6168 mL	1.2335 mL	6.1675 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc