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EGFR-IN-142

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Catalog No. T204227

EGFR-IN-142 (compound 9a) is an EGFR inhibitor with an IC50 value of 0.08 μM. It exhibits antiproliferative activity against MCF-7 cells (IC50 = 3.31 μM) and WI-38 cells (IC50 = 43.99 μM).

EGFR-IN-142

EGFR-IN-142

😃Good
Catalog No. T204227
EGFR-IN-142 (compound 9a) is an EGFR inhibitor with an IC50 value of 0.08 μM. It exhibits antiproliferative activity against MCF-7 cells (IC50 = 3.31 μM) and WI-38 cells (IC50 = 43.99 μM).
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Product Introduction

Bioactivity
Description
EGFR-IN-142 (compound 9a) is an EGFR inhibitor with an IC50 value of 0.08 μM. It exhibits antiproliferative activity against MCF-7 cells (IC50 = 3.31 μM) and WI-38 cells (IC50 = 43.99 μM).
Chemical Properties
Molecular Weight676.923
FormulaC24H20N8O2S7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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