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MSX-127

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Catalog No. T4032Cas No. 6616-56-4
Alias MSX 127

MSX-127 elicites positive response in peptide CXCR4.

MSX-127

MSX-127

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Purity: 98.43%
Catalog No. T4032Alias MSX 127Cas No. 6616-56-4
MSX-127 elicites positive response in peptide CXCR4.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$41In StockIn Stock
10 mg$67In StockIn Stock
25 mg$118In StockIn Stock
50 mg$190In StockIn Stock
100 mg$283In StockIn Stock
200 mg$415In StockIn Stock
1 mL x 10 mM (in DMSO)$47In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.43%
Appearance:Solid
Color:White
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Product Introduction

MSX-127 AI Summary
MSX-127 displaces biotinylated TN14003 from CXCR4 in MDA-MB-231 cells with an IC50 value greater than 1000.0 nM. It is being evaluated for its competitive binding activity against the SDF-1 binding domain of the CXCR4 receptor. In a competitive binding assay, high-affinity compounds resulted in only blue nuclear staining, indicating efficient binding to the CXCR4 receptor. The data suggests that MSX-127 has a weak affinity for the CXCR4 receptor..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
MSX-127 elicites positive response in peptide CXCR4.
SynonymsMSX 127
Chemical Properties
Molecular Weight308.37
FormulaC16H24N2O4
Cas No.6616-56-4
SmilesOc1cc(CN2CCOCC2)c(O)cc1CN1CCOCC1
Relative Density.1.278g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 12 mg/mL (38.91 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.2429 mL16.2143 mL32.4286 mL162.1429 mL
5 mM0.6486 mL3.2429 mL6.4857 mL32.4286 mL
10 mM0.3243 mL1.6214 mL3.2429 mL16.2143 mL
20 mM0.1621 mL0.8107 mL1.6214 mL8.1071 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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