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AMXT1501

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Catalog No. T69249Cas No. 441022-64-6
Alias AMXT-1501

AMXT1501 is a novel inhibitor of the polyamine transport system. It inhibits tumor growth in immunocompetent mice but not in athymic nude mice deficient in T cells .

AMXT1501

AMXT1501

Copy Product Info
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Catalog No. T69249Alias AMXT-1501Cas No. 441022-64-6
AMXT1501 is a novel inhibitor of the polyamine transport system. It inhibits tumor growth in immunocompetent mice but not in athymic nude mice deficient in T cells .
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$299-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Description
AMXT1501 is a novel inhibitor of the polyamine transport system. It inhibits tumor growth in immunocompetent mice but not in athymic nude mice deficient in T cells .
SynonymsAMXT-1501
Chemical Properties
Molecular Weight568.92
FormulaC32H68N6O2
Cas No.441022-64-6
SmilesC([C@H](C(NCCCNCCCCNCCCN)=O)N)CCCNC(CCCCCCCCCCCCCCC)=O
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 80 mg/mL (140.62 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.7577 mL8.7886 mL17.5772 mL87.8858 mL
5 mM0.3515 mL1.7577 mL3.5154 mL17.5772 mL
10 mM0.1758 mL0.8789 mL1.7577 mL8.7886 mL
20 mM0.0879 mL0.4394 mL0.8789 mL4.3943 mL
50 mM0.0352 mL0.1758 mL0.3515 mL1.7577 mL
100 mM0.0176 mL0.0879 mL0.1758 mL0.8789 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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