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Allethrin

Allethrin
Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent.
Catalog No. T25049Cas No. 584-79-2
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Purity:98.19%
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Allethrin

Catalog No. T25049Cas No. 584-79-2

Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
10 mg$30In Stock
25 mg$47In Stock
50 mg$68In Stock
100 mg$98In Stock
200 mg$143In Stock
500 mg$243In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Product Introduction

Bioactivity
Description
Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent.
In vitro
Allethrin (125 μM) induces BCL-2, caspase-3 activation and release of intracellular calcium[1]. Morphological analyses of LC540 cells treated with Allethrin (125 μM) reveals the presence of apoptotic bodies. The percentage of cells displaying early apoptotic features increased significantly[1].
In vivo
In male wistar rats aged 90 day,s Allethrin (25, 50, 100, and 150 mg/kg; every day for 60 days) increased lipid peroxidation in the caput, cauda, and testes[3]. Significant increase in catalase activity was observed in the cauda obtained from 50, 100, and 150 mg/kg. GPx activity was significantly increased in the caput obtained from 150 mg/kg treated rats. In the cauda, it was found to be increased significantly in the 50 and 100 mg/kg treated groups. In contrast, the activity of GPx activity was significantly decreased in the testes of rats treated with 150 mg/kg. GST activity was found to be increased significantly in a dose dependent manner in the caput and cauda of allethrin treated rats[2].
Chemical Properties
Molecular Weight302.41
FormulaC19H26O3
Cas No.584-79-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/ml (198.41 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3068 mL16.5338 mL33.0677 mL165.3384 mL
5 mM0.6614 mL3.3068 mL6.6135 mL33.0677 mL
10 mM0.3307 mL1.6534 mL3.3068 mL16.5338 mL
20 mM0.1653 mL0.8267 mL1.6534 mL8.2669 mL
50 mM0.0661 mL0.3307 mL0.6614 mL3.3068 mL
100 mM0.0331 mL0.1653 mL0.3307 mL1.6534 mL

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