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Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $30 | In Stock | |
25 mg | $47 | In Stock | |
50 mg | $68 | In Stock | |
100 mg | $98 | In Stock | |
200 mg | $143 | In Stock | |
500 mg | $243 | In Stock | |
1 mL x 10 mM (in DMSO) | $39 | In Stock |
Description | Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent. |
In vitro | Allethrin (125 μM) induces BCL-2, caspase-3 activation and release of intracellular calcium[1]. Morphological analyses of LC540 cells treated with Allethrin (125 μM) reveals the presence of apoptotic bodies. The percentage of cells displaying early apoptotic features increased significantly[1]. |
In vivo | In male wistar rats aged 90 day,s Allethrin (25, 50, 100, and 150 mg/kg; every day for 60 days) increased lipid peroxidation in the caput, cauda, and testes[3]. Significant increase in catalase activity was observed in the cauda obtained from 50, 100, and 150 mg/kg. GPx activity was significantly increased in the caput obtained from 150 mg/kg treated rats. In the cauda, it was found to be increased significantly in the 50 and 100 mg/kg treated groups. In contrast, the activity of GPx activity was significantly decreased in the testes of rats treated with 150 mg/kg. GST activity was found to be increased significantly in a dose dependent manner in the caput and cauda of allethrin treated rats[2]. |
Molecular Weight | 302.41 |
Formula | C19H26O3 |
Cas No. | 584-79-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 60 mg/ml (198.41 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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