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L-Thyroxine

L-Thyroxine
L-Thyroxine (NSC 36397) is the major hormone derived from the thyroid gland. L-Thyroxine (NSC 36397) is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. L-Thyroxine (NSC 36397) is released from thyroglobulin by proteolysis and secreted into the blood. L-Thyroxine (NSC 36397) is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
Catalog No. T0864Cas No. 51-48-9
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Purity:98.64%
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L-Thyroxine

Catalog No. T0864Cas No. 51-48-9

L-Thyroxine (NSC 36397) is the major hormone derived from the thyroid gland. L-Thyroxine (NSC 36397) is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. L-Thyroxine (NSC 36397) is released from thyroglobulin by proteolysis and secreted into the blood. L-Thyroxine (NSC 36397) is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
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Pack SizePriceAvailabilityQuantity
200 mg$31In Stock
500 mg$53In Stock
1 g$67In Stock
1 mL x 10 mM (in DMSO)$57In Stock
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Product Introduction

Bioactivity
Description
L-Thyroxine (NSC 36397) is the major hormone derived from the thyroid gland. L-Thyroxine (NSC 36397) is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. L-Thyroxine (NSC 36397) is released from thyroglobulin by proteolysis and secreted into the blood. L-Thyroxine (NSC 36397) is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
AliasLevothyroxine, NSC 36397, T4
Chemical Properties
Molecular Weight776.87
FormulaC15H11I4NO4
Cas No.51-48-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 93 mg/mL (119.7 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.2872 mL6.4361 mL12.8722 mL64.3608 mL
5 mM0.2574 mL1.2872 mL2.5744 mL12.8722 mL
10 mM0.1287 mL0.6436 mL1.2872 mL6.4361 mL
20 mM0.0644 mL0.3218 mL0.6436 mL3.2180 mL
50 mM0.0257 mL0.1287 mL0.2574 mL1.2872 mL
100 mM0.0129 mL0.0644 mL0.1287 mL0.6436 mL

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