Shopping Cart
Remove All
Your shopping cart is currently empty
5-Fluoromethylornithine dihydrochloride
Copy Product Info
😃Good
Catalog No. T78197Cas No. 124796-41-4
Alias 5-FMOrn dihydrochloride
5-Fluoromethylornithine dihydrochloride (5-FMOrn dihydrochloride) is a selective inhibitor of L-Ornithine:2-oxoacid aminotransferase (OAT) and a specific inactivator of OAT, which can be used to study metabolic diseases and neurological diseases.
5-Fluoromethylornithine dihydrochloride
Copy Product Info😃Good
Catalog No. T78197Alias 5-FMOrn dihydrochlorideCas No. 124796-41-4
5-Fluoromethylornithine dihydrochloride (5-FMOrn dihydrochloride) is a selective inhibitor of L-Ornithine:2-oxoacid aminotransferase (OAT) and a specific inactivator of OAT, which can be used to study metabolic diseases and neurological diseases.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $142 | In Stock | In Stock | |
| 5 mg | $355 | In Stock | In Stock | |
| 10 mg | $528 | - | In Stock | |
| 25 mg | $855 | - | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Appearance:Solid
Color:White
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | 5-Fluoromethylornithine dihydrochloride (5-FMOrn dihydrochloride) is a selective inhibitor of L-Ornithine:2-oxoacid aminotransferase (OAT) and a specific inactivator of OAT, which can be used to study metabolic diseases and neurological diseases. |
| In vitro | Incubation for 1 h of L-ornithine carbamoyltransferase, ODC and GABA-T preparations with up to 10 mM 5-Fluoromethylornithine and subsequent determination of the residual enzyme activity demonstrated that none of these enzymes was inactivated. 5-Fluoromethylornithine is a poor substrate of ODC; at 10 mM 5-Fluoromethylornithine, 0.04 nmol of 1-fluoromethylputrescine was formed/h per mg of protein. [1] |
| In vivo | After intraperitoneal administration of 10 mg of 5-Fluoromethylornithine /kg, there is a rapid decrease of OAT activity in all organs, to a basal value. The time-dependence of the effect of 5-Fluoromethylornithine in brain. Minimum activity was usually observed between 2 and 24 h after 5-Fluoromethylornithine administration, thereafter OAT activity recovered gradually. [1] |
| Synonyms | 5-FMOrn dihydrochloride |
| Molecular Weight | 237.1 |
| Formula | C6H15Cl2FN2O2 |
| Cas No. | 124796-41-4 |
| Smiles | O=C(C(CCC(CF)N)N)O.Cl.Cl |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 80 mg/mL (337.41 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (8.44 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy 5-Fluoromethylornithine dihydrochloride | purchase 5-Fluoromethylornithine dihydrochloride | 5-Fluoromethylornithine dihydrochloride cost | order 5-Fluoromethylornithine dihydrochloride | 5-Fluoromethylornithine dihydrochloride chemical structure | 5-Fluoromethylornithine dihydrochloride in vivo | 5-Fluoromethylornithine dihydrochloride in vitro | 5-Fluoromethylornithine dihydrochloride formula | 5-Fluoromethylornithine dihydrochloride molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.