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(1S,4R)-N-Desmethyl Sertraline Hydrochloride

Name: (1S,4R)-N-Desmethyl Sertraline Hydrochloride
Brand: TargetMol
SKU: T9395
Price: 118 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9395Cas No. 675126-07-5

(1S,4R)-N-DesmethylSertralineHydrochloride is a Serotonin transporter and Norepinephrine transporter inhibitor with IC50 of 19 nM and 35 nM, respectively.

(1S,4R)-N-Desmethyl Sertraline Hydrochloride

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Purity: 99.71%

Catalog No. T9395Cas No. 675126-07-5

(1S,4R)-N-DesmethylSertralineHydrochloride is a Serotonin transporter and Norepinephrine transporter inhibitor with IC50 of 19 nM and 35 nM, respectively.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$118	In Stock	In Stock
5 mg	$280	In Stock	In Stock
10 mg	$410	In Stock	In Stock
25 mg	$642	In Stock	In Stock
50 mg	$870	In Stock	In Stock
100 mg	$1,170	In Stock	In Stock
200 mg	$1,570	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$275	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.71%

ee:100%

Appearance:Solid

Color:White

Resource Download

COA CSFC HNMR LCMS

Product Introduction

Bioactivity

Description

(1S,4R)-N-DesmethylSertralineHydrochloride is a Serotonin transporter and Norepinephrine transporter inhibitor with IC50 of 19 nM and 35 nM, respectively.

Chemical Properties

Molecular Weight	328.66
Formula	C₁₆H₁₆Cl₃N
Cas No.	675126-07-5
Smiles	[H]Cl.N[C@@H]1CC[C@@H](C2=CC=C(Cl)C(Cl)=C2)C3=C1C=CC=C3
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (182.56 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0427 mL	15.2133 mL	30.4266 mL	152.1329 mL
5 mM	0.6085 mL	3.0427 mL	6.0853 mL	30.4266 mL
10 mM	0.3043 mL	1.5213 mL	3.0427 mL	15.2133 mL
20 mM	0.1521 mL	0.7607 mL	1.5213 mL	7.6066 mL
50 mM	0.0609 mL	0.3043 mL	0.6085 mL	3.0427 mL
100 mM	0.0304 mL	0.1521 mL	0.3043 mL	1.5213 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

N-Desmethyl Sertraline Hydrochloride(1S,4R)NDesmethyl Sertraline Hydrochloride(1S,4R) N Desmethyl Sertraline Hydrochloride

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