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Norgestimate metabolite Norelgestromin

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Catalog No. T16338Cas No. 53016-31-2
Alias 17-Deacylnorgestimate, 17-Deacetyl norgestimate

Norgestimate metabolite Norelgestromin (17-Deacylnorgestimate) is one of the active metabolites of norgestimate.It is a steroidal progestin used in contraceptive patches, where it is combined with the estrogen ethinyl estradiol.

Norgestimate metabolite Norelgestromin

Norgestimate metabolite Norelgestromin

🥰Excellent
Purity: 99.64%
Catalog No. T16338Alias 17-Deacylnorgestimate, 17-Deacetyl norgestimateCas No. 53016-31-2
Norgestimate metabolite Norelgestromin (17-Deacylnorgestimate) is one of the active metabolites of norgestimate.It is a steroidal progestin used in contraceptive patches, where it is combined with the estrogen ethinyl estradiol.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$30In StockIn Stock
25 mg$58In StockIn Stock
50 mg$111In StockIn Stock
100 mg$163In StockIn Stock
200 mg$243-In Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.64%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
Norgestimate metabolite Norelgestromin (17-Deacylnorgestimate) is one of the active metabolites of norgestimate.It is a steroidal progestin used in contraceptive patches, where it is combined with the estrogen ethinyl estradiol.
Synonyms17-Deacylnorgestimate, 17-Deacetyl norgestimate
Chemical Properties
Molecular Weight327.46
FormulaC21H29NO2
Cas No.53016-31-2
SmilesC(C)[C@@]12[C@]([C@]3([C@](CC1)([C@@]4(C(CC3)=CC(=NO)CC4)[H])[H])[H])(CC[C@]2(C#C)O)[H]
Relative Density.1.23 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 22.5 mg/mL (68.71 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.11 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0538 mL15.2690 mL30.5381 mL152.6904 mL
5 mM0.6108 mL3.0538 mL6.1076 mL30.5381 mL
10 mM0.3054 mL1.5269 mL3.0538 mL15.2690 mL
20 mM0.1527 mL0.7635 mL1.5269 mL7.6345 mL
50 mM0.0611 mL0.3054 mL0.6108 mL3.0538 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

Norgestimate metabolite NorelgestrominInhibitorinhibitDrugMetaboliteDrug Metabolite
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