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FOY 251

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Catalog No. T8676Cas No. 71079-09-9

FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.

FOY 251

FOY 251

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Purity: 99.33%
Catalog No. T8676Cas No. 71079-09-9
FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$49In StockIn Stock
5 mg$118In StockIn Stock
10 mg$196In StockIn Stock
25 mg$334In StockIn Stock
50 mg$472In StockIn Stock
100 mg$672-In Stock
500 mg$1,330-In Stock
1 mL x 10 mM (in DMSO)$135In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.33%
Color:White
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Product Introduction

Bioactivity
Description
FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.
In vitro
FOY-251, an active metabolite of camostat mesilate, on sodium transport in the mouse cortical collecting duct cell line (M-1 cells) and on blood pressure in Dahl salt-sensitive rats.?Treatment with camostat mesilate or FOY-251 decreased equivalent current (Ieq) in M-1 cells in a dose-dependent manner and inhibited the protease activity of prostasin in vitro[1].
Chemical Properties
Molecular Weight409.41
FormulaC17H19N3O7S
Cas No.71079-09-9
SmilesCS(O)(=O)=O.NN=CNc1ccc(cc1)C(=O)Oc1ccc(CC(O)=O)cc1
Relative Density.1.36g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 25 mg/mL (61.06 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+90% Corn Oil: 2 mg/mL (4.89 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4425 mL12.2127 mL24.4254 mL122.1270 mL
5 mM0.4885 mL2.4425 mL4.8851 mL24.4254 mL
10 mM0.2443 mL1.2213 mL2.4425 mL12.2127 mL
20 mM0.1221 mL0.6106 mL1.2213 mL6.1063 mL
50 mM0.0489 mL0.2443 mL0.4885 mL2.4425 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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