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Nimucitinib

🥰Excellent
Catalog No. T67907Cas No. 2740557-24-6

Nimucitinib is a Janus kinase (JAK) inhibitor that can be used to treat dry eye and promote tear production.

Nimucitinib

Nimucitinib

🥰Excellent
Purity: 98.71%
Catalog No. T67907Cas No. 2740557-24-6
Nimucitinib is a Janus kinase (JAK) inhibitor that can be used to treat dry eye and promote tear production.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$97In StockIn Stock
2 mg$142In StockIn Stock
5 mg$239In StockIn Stock
10 mg$372In StockIn Stock
25 mg$688In StockIn Stock
50 mg$987In StockIn Stock
100 mg$1,530In StockIn Stock
500 mg$2,970-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:98.71%
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COA HPLC

Product Introduction

Bioactivity
Description
Nimucitinib is a Janus kinase (JAK) inhibitor that can be used to treat dry eye and promote tear production.
Chemical Properties
Molecular Weight480.51
FormulaC25H26F2N6O2
Cas No.2740557-24-6
SmilesN(CC1=CC(F)=CC(F)=C1)C=2C(C(N)=O)=CN=C(NC3=CC(NC(=O)[C@H]4CCCNC4)=CC=C3)C2
Relative Density.1.382 g/cm3 (Predicted)
ColorYellow
AppearanceSolid
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (114.46 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0811 mL10.4056 mL20.8112 mL104.0561 mL
5 mM0.4162 mL2.0811 mL4.1622 mL20.8112 mL
10 mM0.2081 mL1.0406 mL2.0811 mL10.4056 mL
20 mM0.1041 mL0.5203 mL1.0406 mL5.2028 mL
50 mM0.0416 mL0.2081 mL0.4162 mL2.0811 mL
100 mM0.0208 mL0.1041 mL0.2081 mL1.0406 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

NimucitinibJAK
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