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BIM-46187 4HCl

Name: BIM-46187 4HCl
Brand: TargetMol
SKU: T16519L
Price: 147 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T16519LCas No. 2489449-03-6

Alias PH-064 4HCl

BIM-46187 4HCl (PH-064 4HCl) is a heterotrimeric G-protein complex inhibitor.

BIM-46187 4HCl

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Purity: 99.63%

Catalog No. T16519LAlias PH-064 4HClCas No. 2489449-03-6

BIM-46187 4HCl (PH-064 4HCl) is a heterotrimeric G-protein complex inhibitor.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$147	In Stock	In Stock
2 mg	$198	In Stock	In Stock
5 mg	$298	In Stock	In Stock
10 mg	$443	In Stock	In Stock
25 mg	$732	In Stock	In Stock
50 mg	$987	In Stock	In Stock
100 mg	$1,390	In Stock	In Stock
500 mg	$2,790	-	In Stock
1 mL x 10 mM (in DMSO)	$523	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Questions

Batch Information

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Purity:99.63%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	BIM-46187 4HCl (PH-064 4HCl) is a heterotrimeric G-protein complex inhibitor.
Synonyms	PH-064 4HCl

Chemical Properties

Molecular Weight	940.95
Formula	C₄₄H₆₂Cl₄N₈O₂S₂
Cas No.	2489449-03-6
Smiles	O=C([C@@H](N)CSSC[C@H](N)C(N(CCN1C2=NC(C3=CC=CC=C3)=C1)[C@H]2CC4CCCCC4)=O)N5[C@H](C6=NC(C7=CC=CC=C7)=CN6CC5)CC8CCCCC8.Cl.Cl.Cl.Cl
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 127.5 mg/mL (135.5 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.0628 mL	5.3138 mL	10.6276 mL	53.1378 mL
5 mM	0.2126 mL	1.0628 mL	2.1255 mL	10.6276 mL
10 mM	0.1063 mL	0.5314 mL	1.0628 mL	5.3138 mL
20 mM	0.0531 mL	0.2657 mL	0.5314 mL	2.6569 mL
50 mM	0.0213 mL	0.1063 mL	0.2126 mL	1.0628 mL
100 mM	0.0106 mL	0.0531 mL	0.1063 mL	0.5314 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc