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Ribostamycin sulfate
🥰Excellent
Catalog No. T1214Cas No. 53797-35-6
Alias Vistamycin sulfate
Ribostamycin sulfate (Vistamycin sulfate) , an aminoglycoside antibiotic, contains a neutral sugar moiety and is produced by Streptomyces ribosome.
Ribostamycin sulfate
🥰Excellent
Purity: 99.57%
Catalog No. T1214Alias Vistamycin sulfateCas No. 53797-35-6
Ribostamycin sulfate (Vistamycin sulfate) , an aminoglycoside antibiotic, contains a neutral sugar moiety and is produced by Streptomyces ribosome.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $42 | In Stock | |
| 50 mg | $59 | In Stock | |
| 100 mg | $89 | In Stock | |
| 500 mg | $219 | In Stock |
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Purity:99.57%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Ribostamycin sulfate (Vistamycin sulfate) , an aminoglycoside antibiotic, contains a neutral sugar moiety and is produced by Streptomyces ribosome. |
| In vitro | Ribostamycin, as an intermediate in the biosynthesis of neomycin, can inhibit the chaperone activity of protein disulfide isomerase (PDI) but does not inhibit its isomerase activity. At a concentration of 256 µg/mL, it exhibits almost no toxicity to HUVEC cells. |
| In vivo | Compared to other antibiotics, Ribostamycin (400 mg/kg/day) causes the lowest ototoxicity, as its drug concentration in the inner ear fluid of guinea pigs is relatively low. Ribostamycin exhibits the least ototoxicity to the cochlea and vestibular organs of guinea pigs. |
| Alias | Vistamycin sulfate |
| Molecular Weight | 552.55 |
| Formula | C17H34N4O10·H2SO4 |
| Cas No. | 53797-35-6 |
| Smiles | OS(O)(=O)=O.NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)[C@H](N)[C@@H](O)[C@@H]1O |
| Relative Density. | 1.6g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: Insoluble H2O: 100 mg/mL (180.98 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10%DMSO + 90% Saline: 100 mg/mL (180.98 mM), Sonication is recommended. PBS: 100 mg/mL (180.98 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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