Shopping Cart

Your shopping cart is currently empty

Ribostamycin sulfate

Name: Ribostamycin sulfate
Brand: TargetMol
SKU: T1214
Price: 38 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T1214Cas No. 53797-35-6

Alias Vistamycin sulfate

Ribostamycin sulfate (Vistamycin sulfate) , an aminoglycoside antibiotic, contains a neutral sugar moiety and is produced by Streptomyces ribosome.

Ribostamycin sulfate

🥰Excellent

Purity: 99.57%

Catalog No. T1214Alias Vistamycin sulfateCas No. 53797-35-6

Ribostamycin sulfate (Vistamycin sulfate) , an aminoglycoside antibiotic, contains a neutral sugar moiety and is produced by Streptomyces ribosome.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$38	In Stock	In Stock
50 mg	$53	In Stock	In Stock
100 mg	$81	In Stock	In Stock
500 mg	$198	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.57%

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Ribostamycin sulfate (Vistamycin sulfate) , an aminoglycoside antibiotic, contains a neutral sugar moiety and is produced by Streptomyces ribosome.
In vitro	Ribostamycin, as an intermediate in the biosynthesis of neomycin, can inhibit the chaperone activity of protein disulfide isomerase (PDI) but does not inhibit its isomerase activity. At a concentration of 256 µg/mL, it exhibits almost no toxicity to HUVEC cells.
In vivo	Compared to other antibiotics, Ribostamycin (400 mg/kg/day) causes the lowest ototoxicity, as its drug concentration in the inner ear fluid of guinea pigs is relatively low. Ribostamycin exhibits the least ototoxicity to the cochlea and vestibular organs of guinea pigs.
Synonyms	Vistamycin sulfate

Chemical Properties

Molecular Weight	552.55
Formula	C₁₇H₃₄N₄O₁₀·H₂SO₄
Cas No.	53797-35-6
Smiles	OS(O)(=O)=O.NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)[C@H](N)[C@@H](O)[C@@H]1O
Relative Density.	1.6g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: Insoluble

H2O: 100 mg/mL (180.98 mM), Sonication is recommended.

In Vivo Formulation

10%DMSO + 90% Saline: 100 mg/mL (180.98 mM), Sonication is recommended.

PBS: 100 mg/mL (180.98 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	1.8098 mL	9.0490 mL	18.0979 mL	90.4895 mL
5 mM	0.3620 mL	1.8098 mL	3.6196 mL	18.0979 mL
10 mM	0.1810 mL	0.9049 mL	1.8098 mL	9.0490 mL
20 mM	0.0905 mL	0.4524 mL	0.9049 mL	4.5245 mL
50 mM	0.0362 mL	0.1810 mL	0.3620 mL	1.8098 mL
100 mM	0.0181 mL	0.0905 mL	0.1810 mL	0.9049 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc