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M7594_0037

Name: M7594_0037
Brand: TargetMol
SKU: T27969
Price: 117 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T27969Cas No. 774551-07-4

Alias M7594-0037, M75940037, M7594 0037

M7594_0037 is an inhibitor of Human peptide deformylase (HsPDF) and can be used in studies about anticancer.

M7594_0037

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Purity: 99.58%

Catalog No. T27969Alias M7594-0037, M75940037, M7594 0037Cas No. 774551-07-4

M7594_0037 is an inhibitor of Human peptide deformylase (HsPDF) and can be used in studies about anticancer.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$117	In Stock	In Stock
2 mg	$176	In Stock	In Stock
5 mg	$269	In Stock	In Stock
10 mg	$395	In Stock	In Stock
25 mg	$592	In Stock	In Stock
50 mg	$828	In Stock	In Stock
100 mg	$1,130	In Stock	In Stock
200 mg	$1,520	-	In Stock
1 mL x 10 mM (in DMSO)	$291	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.58%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	M7594_0037 is an inhibitor of Human peptide deformylase (HsPDF) and can be used in studies about anticancer.
In vitro	M7594_0037 exhibits potent anticancer activities against HeLa, A549 and MCF-7 cell lines with IC50s of 35.26, 29.63 and 24.63 μM, respectively[1].
Synonyms	M7594-0037, M75940037, M7594 0037

Chemical Properties

Molecular Weight	387.86
Formula	C₂₀H₂₂ClN₃O₃
Cas No.	774551-07-4
Smiles	COC1=CC(CNCCC2=CNC3=CC=CC=C23)=CC(Cl)=C1OCC(N)=O
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (128.91 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5782 mL	12.8912 mL	25.7825 mL	128.9125 mL
5 mM	0.5156 mL	2.5782 mL	5.1565 mL	25.7825 mL
10 mM	0.2578 mL	1.2891 mL	2.5782 mL	12.8912 mL
20 mM	0.1289 mL	0.6446 mL	1.2891 mL	6.4456 mL
50 mM	0.0516 mL	0.2578 mL	0.5156 mL	2.5782 mL
100 mM	0.0258 mL	0.1289 mL	0.2578 mL	1.2891 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc