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Estrone sulfate sodium

Name: Estrone sulfate sodium
Brand: TargetMol
SKU: T36857
Price: 33 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T36857Cas No. 438-67-5

Alias Estrone 3-sulfate (sodium salt), 17β-Estrone 3-sulfate

Estrone sulfate sodium (17β-Estrone 3-sulfate) is an endogenous steroid and an estrogen ester that is biologically inactive. It is converted by steroid sulfatase into estrone . Estrone sulfate sodium has been investigated as a ligand for targeting organic anion transporting polypeptides f

Estrone sulfate sodium

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Purity: 99.88%

Catalog No. T36857Alias Estrone 3-sulfate (sodium salt), 17β-Estrone 3-sulfateCas No. 438-67-5

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$33	In Stock	In Stock
5 mg	$52	In Stock	In Stock
10 mg	$85	In Stock	In Stock
25 mg	$172	-	In Stock
50 mg	$322	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.88%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

Estrone sulfate sodium AI Summary

Estrone sulfate sodium exhibits diverse bioactivities, including notable antifungal and antibacterial properties. It shows antifungal activity against Candida albicans with 3.72% inhibition, while exhibiting -4.65% inhibition against Cryptococcus neoformans, which may indicate a potential stimulatory effect on this organism. In terms of antibacterial activity, the compound inhibits Escherichia coli by 6.3%, Klebsiella pneumoniae by 1.74%, Pseudomonas aeruginosa by 7.52%, Acinetobacter baumannii by 14.02%, and Staphylococcus aureus MRSA by 8.52%. These results suggest that Estrone sulfate sodium may be more effective against certain bacterial strains, particularly Acinetobacter baumannii..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Estrone sulfate sodium (17β-Estrone 3-sulfate) is an endogenous steroid and an estrogen ester that is biologically inactive. It is converted by steroid sulfatase into estrone . Estrone sulfate sodium has been investigated as a ligand for targeting organic anion transporting polypeptides f
Synonyms	Estrone 3-sulfate (sodium salt), 17β-Estrone 3-sulfate

Chemical Properties

Molecular Weight	372.41
Formula	C₁₈H₂₁NaO₅S
Cas No.	438-67-5
Smiles	O=C1CC[C@@]2([H])[C@]3([H])CCC4=C(C=CC(OS(=O)([O-])=O)=C4)[C@@]3([H])CC[C@]12C.[Na+]

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 30 mg/mL (80.56 mM), Sonication and heating to 60℃ are recommended.

Ethanol: 2 mg/mL (5.37 mM), Sonication is recommended.

DMF: 30 mg/mL (80.56 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.37 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO/DMF

	1mg	5mg	10mg	50mg
1 mM	2.6852 mL	13.4261 mL	26.8521 mL	134.2606 mL
5 mM	0.5370 mL	2.6852 mL	5.3704 mL	26.8521 mL

DMSO/DMF

	1mg	5mg	10mg	50mg
10 mM	0.2685 mL	1.3426 mL	2.6852 mL	13.4261 mL
20 mM	0.1343 mL	0.6713 mL	1.3426 mL	6.7130 mL
50 mM	0.0537 mL	0.2685 mL	0.5370 mL	2.6852 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc