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Hydroxystilbamidine bis(methanesulfonate)
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Catalog No. T19014Cas No. 223769-64-0
Hydroxystilbamidine bis(methanesulfonate) is a fluorescent cationic dye that binds strongly to DNA and RNA, and is widely used as a retrograde neuronal tracer, while also acting as a potent inhibitor of cellular ribonucleases, making it a versatile research reagent for neuroanatomical tracing, nucleic acid labeling, and studies of RNA stability and degradation.
Hydroxystilbamidine bis(methanesulfonate)
😃Good
Catalog No. T19014Cas No. 223769-64-0
Hydroxystilbamidine bis(methanesulfonate) is a fluorescent cationic dye that binds strongly to DNA and RNA, and is widely used as a retrograde neuronal tracer, while also acting as a potent inhibitor of cellular ribonucleases, making it a versatile research reagent for neuroanatomical tracing, nucleic acid labeling, and studies of RNA stability and degradation.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | $693 | 35 days | 35 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Chemical Properties
Storage & Solubility Information
| Description | Hydroxystilbamidine bis(methanesulfonate) is a fluorescent cationic dye that binds strongly to DNA and RNA, and is widely used as a retrograde neuronal tracer, while also acting as a potent inhibitor of cellular ribonucleases, making it a versatile research reagent for neuroanatomical tracing, nucleic acid labeling, and studies of RNA stability and degradation. |
| In vitro | The trypanocidal dye Hydroxystilbamidine bis(methanesulfonate) facilitates mRNA recovery following polysome release with Nonidet P-40 (NP-40), as analyzed by sucrose gradient distribution of detergent-lysed postnuclear supernates [1]. |
| In vivo | In mouse models immunized with Sheep Red Blood Cells (SRBC),Hydroxystilbamidine bis(methanesulfonate) has been evaluated for its effects on the immune response. Administration of the compound is associated with a reduction in the count of Plaque-Forming Cells (PFC) [2]. |
| Molecular Weight | 376.43 |
| Formula | C17H20N4O4S |
| Cas No. | 223769-64-0 |
| Smiles | O=S(=O)(O)C.N=C(N)C1=CC=C(C=C1)C=CC2=CC=C(C=C2O)C(=N)N |
| Relative Density. | no data available |
| Storage | keep away from moisture,keep away from direct sunlight | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 40 mg/mL (106.26 mM), Sonication is recommended. DMSO: 40 mg/mL (106.26 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O/DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSO (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyThe above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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