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Fosdevirine

Name: Fosdevirine
Brand: TargetMol
SKU: T31860
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

😃Good

Catalog No. T31860Cas No. 1018450-26-4

Alias IDX-12899, IDX 899, GSK-2248761A, GSK2248761A, GSK-2248761, GSK2248761, GSK 2248761A, GSK 2248761, FDV

Fosdevirine (GSK2248761) is a selective and potent non-nucleoside reverse transcriptase (NNRTI) inhibitor with anti-HIV activity for the study of neurological related disorders such as late-onset epilepsy.

Fosdevirine

😃Good

Purity: 99.92%

Catalog No. T31860Alias IDX-12899, IDX 899, GSK-2248761A, GSK2248761A, GSK-2248761, GSK2248761, GSK 2248761A, GSK 2248761, FDVCas No. 1018450-26-4

Pack Size	Price	Availability
1 mg	$195	In Stock
5 mg	$483	In Stock
10 mg	$692	In Stock
25 mg	$1,080	6-8weeks
50 mg	$1,490	6-8weeks

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Purity:99.92%

ee:99.58%

Resource Download

COA CSFC HNMR HPLC LCMS ORP PNMR

Product Introduction

Bioactivity

Description	Fosdevirine (GSK2248761) is a selective and potent non-nucleoside reverse transcriptase (NNRTI) inhibitor with anti-HIV activity for the study of neurological related disorders such as late-onset epilepsy.
In vitro	Fosdevirine demonstrates potent in vitro antiviral efficacy against single-point mutations K103N and Y181C, and is similarly effective against the majority of double mutants[1].
Alias	IDX-12899, IDX 899, GSK-2248761A, GSK2248761A, GSK-2248761, GSK2248761, GSK 2248761A, GSK 2248761, FDV

Chemical Properties

Molecular Weight	413.79
Formula	C₂₀H₁₇ClN₃O₃P
Cas No.	1018450-26-4
Smiles	P(OC)(=O)(C=1C=2C(NC1C(N)=O)=CC=C(Cl)C2)C3=CC(/C=C/C#N)=CC(C)=C3
Relative Density.	1.42 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc