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ELQ-300

🥰Excellent
Catalog No. T5477Cas No. 1354745-52-0

ELQ-300 is bioavailable antimalarial agent, acts as an inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (cyt bc1)

ELQ-300

ELQ-300

🥰Excellent
Purity: 97.28%
Catalog No. T5477Cas No. 1354745-52-0
ELQ-300 is bioavailable antimalarial agent, acts as an inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (cyt bc1)
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$35In StockIn Stock
5 mg$59In StockIn Stock
10 mg$95In StockIn Stock
25 mg$193In StockIn Stock
50 mg$278In StockIn Stock
100 mg$387In StockIn Stock
200 mg$549-In Stock
1 mL x 10 mM (in DMSO)$59In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:97.28%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
ELQ-300 is bioavailable antimalarial agent, acts as an inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (cyt bc1)
Chemical Properties
Molecular Weight475.84
FormulaC24H17ClF3NO4
Cas No.1354745-52-0
SmilesCOc1cc2[nH]c(C)c(-c3ccc(Oc4ccc(OC(F)(F)F)cc4)cc3)c(=O)c2cc1Cl
Relative Density.1.362 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 15.62 mg/mL (32.83 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1015 mL10.5077 mL21.0155 mL105.0773 mL
5 mM0.4203 mL2.1015 mL4.2031 mL21.0155 mL
10 mM0.2102 mL1.0508 mL2.1015 mL10.5077 mL
20 mM0.1051 mL0.5254 mL1.0508 mL5.2539 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

recrudescenceParasiteoralmiceInhibitorinhibitinfectionELQ-300ELQ300ELQ 300antimalarialacute
Related Tags: buy ELQ-300 | purchase ELQ-300 | ELQ-300 cost | order ELQ-300 | ELQ-300 chemical structure | ELQ-300 formula | ELQ-300 molecular weight
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