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NO-711ME

🥰Excellent
Catalog No. T24540Cas No. 127586-66-7
Alias NO711ME, N-O711 Methyl ester, NO711 Methyl ester, N O711 Methyl ester

NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.

NO-711ME

NO-711ME

🥰Excellent
Purity: 99.54%
Catalog No. T24540Alias NO711ME, N-O711 Methyl ester, NO711 Methyl ester, N O711 Methyl esterCas No. 127586-66-7
NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.
Pack SizePriceAvailabilityQuantity
1 mg$62In Stock
5 mg$138In Stock
10 mg$209In Stock
25 mg$333In Stock
50 mg$475In Stock
100 mg$638In Stock
200 mg$853In Stock
1 mL x 10 mM (in DMSO)$148In Stock
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Purity:99.54%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.
SynonymsNO711ME, N-O711 Methyl ester, NO711 Methyl ester, N O711 Methyl ester
Chemical Properties
Molecular Weight364.44
FormulaC22H24N2O3
Cas No.127586-66-7
SmilesC(=NOCCN1CC(C(OC)=O)=CCC1)(C2=CC=CC=C2)C3=CC=CC=C3
Relative Density.1.11 g/cm3 at 20℃
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (123.48 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7439 mL13.7197 mL27.4394 mL137.1968 mL
5 mM0.5488 mL2.7439 mL5.4879 mL27.4394 mL
10 mM0.2744 mL1.3720 mL2.7439 mL13.7197 mL
20 mM0.1372 mL0.6860 mL1.3720 mL6.8598 mL
50 mM0.0549 mL0.2744 mL0.5488 mL2.7439 mL
100 mM0.0274 mL0.1372 mL0.2744 mL1.3720 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

NO-711MENO 711MEGABAReceptorGABA uptakeGABA Receptor
Related Tags: buy NO-711ME | purchase NO-711ME | NO-711ME cost | order NO-711ME | NO-711ME chemical structure | NO-711ME formula | NO-711ME molecular weight
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