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GSK-3 Inhibitor XIII

Name: GSK-3 Inhibitor XIII
Brand: TargetMol
SKU: T78578
Price: 108 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T78578Cas No. 404828-14-4

GSK-3 Inhibitor XIII, an ATP-competitive GSK-3 inhibitor (Ki: 24 nM), can be used to study diabetes and obesity.

GSK-3 Inhibitor XIII

🥰Excellent

Purity: 99.86%

Catalog No. T78578Cas No. 404828-14-4

GSK-3 Inhibitor XIII, an ATP-competitive GSK-3 inhibitor (Ki: 24 nM), can be used to study diabetes and obesity.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$108	In Stock	In Stock
5 mg	$255	In Stock	In Stock
10 mg	$459	In Stock	In Stock
25 mg	$983	In Stock	In Stock
50 mg	$1,350	In Stock	In Stock
100 mg	$1,820	In Stock	In Stock
200 mg	$2,460	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$265	In Stock	In Stock

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Expected start date of shipmentUSA Warehouse [1-2 days] Global Warehouse [5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.86%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description

GSK-3 Inhibitor XIII, an ATP-competitive GSK-3 inhibitor (Ki: 24 nM), can be used to study diabetes and obesity.

Chemical Properties

Molecular Weight	301.35
Formula	C₁₈H₁₅N₅
Cas No.	404828-14-4
Smiles	N=1NC(=CC1NC=2N=C(N=C3C=CC=CC32)C=4C=CC=CC4)C

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (265.47 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (10.95 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3184 mL	16.5920 mL	33.1840 mL	165.9200 mL
5 mM	0.6637 mL	3.3184 mL	6.6368 mL	33.1840 mL
10 mM	0.3318 mL	1.6592 mL	3.3184 mL	16.5920 mL
20 mM	0.1659 mL	0.8296 mL	1.6592 mL	8.2960 mL
50 mM	0.0664 mL	0.3318 mL	0.6637 mL	3.3184 mL
100 mM	0.0332 mL	0.1659 mL	0.3318 mL	1.6592 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc