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Tubulin inhibitor 35

Name: Tubulin inhibitor 35
Brand: TargetMol
SKU: T77584
Price: 54 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T77584Cas No. 2247047-77-2

Alias Tubulin IN 35

Tubulin inhibitor 35 (Tubulin IN 35) is a potent dual inhibitor of topoisomerase I and microtubule protein polymerization with antitumor activity, inhibits migration and invasion of MGC-803 and RKO cell lines, interrupts the cell cycle and induces apoptosis.

Tubulin inhibitor 35

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Purity: 99.45%

Catalog No. T77584Alias Tubulin IN 35Cas No. 2247047-77-2

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$54	In Stock	In Stock
5 mg	$126	In Stock	In Stock
10 mg	$185	In Stock	In Stock
25 mg	$297	In Stock	In Stock
50 mg	$458	In Stock	In Stock
100 mg	$668	In Stock	In Stock
500 mg	$2,350	-	In Stock
1 g	$3,230	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.45%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Tubulin inhibitor 35 (Tubulin IN 35) is a potent dual inhibitor of topoisomerase I and microtubule protein polymerization with antitumor activity, inhibits migration and invasion of MGC-803 and RKO cell lines, interrupts the cell cycle and induces apoptosis.
Synonyms	Tubulin IN 35

Chemical Properties

Molecular Weight	331.41
Formula	C₂₁H₂₁N₃O
Cas No.	2247047-77-2
Smiles	O=C1C=2C=CC=CC2N(CCC)C3C=4NC=5C=CC=CC5C4CCN13
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (150.87 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0174 mL	15.0871 mL	30.1741 mL	150.8705 mL
5 mM	0.6035 mL	3.0174 mL	6.0348 mL	30.1741 mL
10 mM	0.3017 mL	1.5087 mL	3.0174 mL	15.0871 mL
20 mM	0.1509 mL	0.7544 mL	1.5087 mL	7.5435 mL
50 mM	0.0603 mL	0.3017 mL	0.6035 mL	3.0174 mL
100 mM	0.0302 mL	0.1509 mL	0.3017 mL	1.5087 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc