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Methylmalonic acid

Name: Methylmalonic acid
Brand: TargetMol
SKU: T4817
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T4817Cas No. 516-05-2

Alias NSC 25201, MMA, Methylpropanedioic acid, Methylmalonate, Isosuccinic acid

Methylmalonic acid is an indicator of vitamin B-12 deficiency in cancer patients.Methylmalonic acid is a competitive succinate dehydrogenase inhibitor.

Methylmalonic acid

🥰Excellent

Purity: 98%

Catalog No. T4817Alias NSC 25201, MMA, Methylpropanedioic acid, Methylmalonate, Isosuccinic acidCas No. 516-05-2

Methylmalonic acid is an indicator of vitamin B-12 deficiency in cancer patients.Methylmalonic acid is a competitive succinate dehydrogenase inhibitor.

Pack Size	Price	USA Warehouse	Global Warehouse
1 g	$33	In Stock	In Stock
2 g	$40	-	In Stock
5 g	$54	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98%

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COA

Product Introduction

Bioactivity

Description	Methylmalonic acid is an indicator of vitamin B-12 deficiency in cancer patients.Methylmalonic acid is a competitive succinate dehydrogenase inhibitor.
Synonyms	NSC 25201, MMA, Methylpropanedioic acid, Methylmalonate, Isosuccinic acid

Chemical Properties

Molecular Weight	118.09
Formula	C₄H₆O₄
Cas No.	516-05-2
Smiles	C(C(O)=O)(C(O)=O)C
Relative Density.	1.45

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 73.8 mg/mL (624.95 mM), Sonication is recommended.

H2O: 100 mg/mL (846.81 mM), Sonication is recommended.

Ethanol: 100 mg/mL (846.81 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (16.94 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO/H2O/Ethanol

	1mg	5mg	10mg	50mg
1 mM	8.4681 mL	42.3406 mL	84.6812 mL	423.4059 mL
5 mM	1.6936 mL	8.4681 mL	16.9362 mL	84.6812 mL
10 mM	0.8468 mL	4.2341 mL	8.4681 mL	42.3406 mL
20 mM	0.4234 mL	2.1170 mL	4.2341 mL	21.1703 mL
50 mM	0.1694 mL	0.8468 mL	1.6936 mL	8.4681 mL
100 mM	0.0847 mL	0.4234 mL	0.8468 mL	4.2341 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc