Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CAY10721 is an inhibitor of sirtuin 3 (SIRT3), a class III HDAC (39% SIRT3 inhibition at 200 μM). Upregulation of SIRT3 transcription is associated with oral squamous cell carcinoma (OSCC) and breast cancer with lymph node involvement, while SIRT3 down-regulation inhibits the growth of OSCC cells and sensitizes them to radiation and chemotherapy.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 78.00 | |
5 mg | 35 days | $ 348.00 | |
10 mg | 35 days | $ 595.00 | |
25 mg | 35 days | $ 1,330.00 |
Description | CAY10721 is an inhibitor of sirtuin 3 (SIRT3), a class III HDAC (39% SIRT3 inhibition at 200 μM). Upregulation of SIRT3 transcription is associated with oral squamous cell carcinoma (OSCC) and breast cancer with lymph node involvement, while SIRT3 down-regulation inhibits the growth of OSCC cells and sensitizes them to radiation and chemotherapy. |
Molecular Weight | 351.38 |
Formula | C18H13N3O3S |
CAS No. | 848688-62-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL
DMF: 30 mg/mL
DMSO:PBS(pH 7.2) (1:4): 0.20 mg/mL
You can also refer to dose conversion for different animals. More
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CAY10721 848688-62-0 CAY 10721 CAY-10721 inhibitor inhibit