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Anisodine

Name: Anisodine
Brand: TargetMol
SKU: T69150
Price: 293 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T69150Cas No. 52646-92-1

Anisodine is an inhibitor of muscarinic acetylcholine receptors (mAChR) with neuroprotective activity, used in research on multiple myeloma and metastatic breast cancer.

Anisodine

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Purity: 99.54%

Catalog No. T69150Cas No. 52646-92-1

Anisodine is an inhibitor of muscarinic acetylcholine receptors (mAChR) with neuroprotective activity, used in research on multiple myeloma and metastatic breast cancer.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$293	-	In Stock
5 mg	$722	-	In Stock
10 mg	$987	-	In Stock
25 mg	$1,520	-	In Stock
50 mg	$1,980	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.54%

ee:99.96%

Color:White to Yellow

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COA CSFC HNMR LCMS ORP

Product Introduction

Bioactivity

Description	Anisodine is an inhibitor of muscarinic acetylcholine receptors (mAChR) with neuroprotective activity, used in research on multiple myeloma and metastatic breast cancer.
Targets&IC50	OCT2:1.8 mM, OCT1:12.9 µM
In vitro	In HEK293 cells, Anisodine inhibited OCT1 and OCT2 with IC50 of 12.9 µmol/L and 1.8 mmol/L, respectively. [1]
In vivo	Anisodine has protective effect on acute forebrain ischemia-reperfusion injury in rats. [2] Anisodine (10 mg/kg, i.p.) can induce forgetfulness in animal models. [3]

Chemical Properties

Molecular Weight	319.35
Formula	C₁₇H₂₁NO₅
Cas No.	52646-92-1
Smiles	CN1[C@@]2([C@]3([C@](O3)([C@]1(C[C@@H](OC([C@](CO)(O)C4=CC=CC=C4)=O)C2)[H])[H])[H])[H]

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (782.84 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1314 mL	15.6568 mL	31.3136 mL	156.5680 mL
5 mM	0.6263 mL	3.1314 mL	6.2627 mL	31.3136 mL
10 mM	0.3131 mL	1.5657 mL	3.1314 mL	15.6568 mL
20 mM	0.1566 mL	0.7828 mL	1.5657 mL	7.8284 mL
50 mM	0.0626 mL	0.3131 mL	0.6263 mL	3.1314 mL
100 mM	0.0313 mL	0.1566 mL	0.3131 mL	1.5657 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc