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kb NB 142-70

Name: kb NB 142-70
Brand: TargetMol
SKU: T2062
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2062Cas No. 1233533-04-4

kb NB 142-70 is a selective protein kinase D (PKD) inhibitor with IC50 values of 28.3 nM, 58.7 nM, and 53.2 nM for PKD1, PKD2, and PKD3 respectively.

kb NB 142-70

🥰Excellent

Purity: 99.64%

Catalog No. T2062Cas No. 1233533-04-4

kb NB 142-70 is a selective protein kinase D (PKD) inhibitor with IC50 values of 28.3 nM, 58.7 nM, and 53.2 nM for PKD1, PKD2, and PKD3 respectively.

Pack Size	Price	Availability
1 mg	$40	In Stock
5 mg	$96	In Stock
10 mg	$156	In Stock
25 mg	$347	In Stock
50 mg	$519	In Stock
100 mg	$743	In Stock
1 mL x 10 mM (in DMSO)	$97	In Stock

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Batch Information

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Purity:99.64%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	kb NB 142-70 is a selective protein kinase D (PKD) inhibitor with IC50 values of 28.3 nM, 58.7 nM, and 53.2 nM for PKD1, PKD2, and PKD3 respectively.
Targets&IC50	PKD1:28.3nM, PKD2:58.7nM, PKD3:53.2 nM

Chemical Properties

Molecular Weight	251.32
Formula	C₁₁H₉NO₂S₂
Cas No.	1233533-04-4
Smiles	Oc1ccc2sc3c(SCCNC3=O)c2c1
Relative Density.	1.495 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 25.13 mg/mL (99.99 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9790 mL	19.8950 mL	39.7899 mL	198.9495 mL
5 mM	0.7958 mL	3.9790 mL	7.9580 mL	39.7899 mL
10 mM	0.3979 mL	1.9895 mL	3.9790 mL	19.8950 mL
20 mM	0.1989 mL	0.9947 mL	1.9895 mL	9.9475 mL
50 mM	0.0796 mL	0.3979 mL	0.7958 mL	3.9790 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc