Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CWI1-2 HCL is an effective IGF2BP2 inhibitor, which can induce apoptosis and differentiation by binding IGF2BP2 and inhibiting its interaction with M6A-modified target transcription, and has therapeutic effects on leukemia.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 51.00 | |
5 mg | In stock | $ 123.00 | |
10 mg | In stock | $ 189.00 | |
25 mg | In stock | $ 369.00 | |
50 mg | In stock | $ 542.00 | |
100 mg | In stock | $ 773.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 158.00 |
Description | CWI1-2 HCL is an effective IGF2BP2 inhibitor, which can induce apoptosis and differentiation by binding IGF2BP2 and inhibiting its interaction with M6A-modified target transcription, and has therapeutic effects on leukemia. |
In vitro | CWI1-2 (0-1 μM, 24 h) hydrochloride exhibits significant anti-leukemia efficacy.[1] |
In vivo | CWI1-2 (5 mg/kg, i.v., once daily, 7-10 days) hydrochloride significantly delays the onset of leukemia and prolongs the survival time in BMT recipient B6.SJL (CD45.1) mice, without significant impact on body weight.[1] |
Molecular Weight | 556.23 |
Formula | C22H18Cl4N6O3 |
CAS No. | 2408590-37-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5 mg/mL (40.45 mM)
You can also refer to dose conversion for different animals. More
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CWI1-2 HCL 2408590-37-2 Apoptosis CWI12HCL inhibitor inhibit