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MC4033

Catalog No. T78156 CAS 28532-21-0

MC4033 exhibits inhibitory concentration 50 (IC50) values of 39.4 µM in HCT116, 52.1 µM in H1299, 41 µM in A549, and 30.1 µM in U937 [1]. Additionally, treatment with MC4033 at concentrations of 25, 50, 100, and 200 µM for 72 hours diminishes H4K16Ac levels in HT29 cells, indicating its potential as a KAT8 inhibitor [1].

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MC4033, CAS 28532-21-0

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Description	MC4033 exhibits inhibitory concentration 50 (IC50) values of 39.4 µM in HCT116, 52.1 µM in H1299, 41 µM in A549, and 30.1 µM in U937 [1]. Additionally, treatment with MC4033 at concentrations of 25, 50, 100, and 200 µM for 72 hours diminishes H4K16Ac levels in HT29 cells, indicating its potential as a KAT8 inhibitor [1].
In vitro	MC4033, at concentrations of 25, 50, 100, and 200 μM for a duration of 72 hours, reduced the expression level of H4K16Ac in HT29 cells, indicating its capacity to suppress the expression of KAT8 within the cells [1]. Furthermore, the IC50 values of MC4033 were determined to be 39.4 μM, 52.1 μM, 41 μM, and 30.1 μM for HCT116, H1299, A549, and U937 cells, respectively [1].

Molecular Weight	295.29
Formula	C16H13N3O3
CAS No.	28532-21-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

MC4033 28532-21-0 Apoptosis inhibitor inhibit

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