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BLU-222

Name: BLU-222
Brand: TargetMol
SKU: T84321
Price: 123 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T84321Cas No. 2888704-84-3

Alias BLU222, BLU 222

BLU-222 is an orally available but selective cell cycle protein-dependent kinase (CDK2) inhibitor with antitumor activity for the study of ovarian and uterine cancer.

BLU-222

🥰Excellent

Purity: 99.92%

Catalog No. T84321Alias BLU222, BLU 222Cas No. 2888704-84-3

BLU-222 is an orally available but selective cell cycle protein-dependent kinase (CDK2) inhibitor with antitumor activity for the study of ovarian and uterine cancer.

Pack Size	Price	Availability
1 mg	$123	In Stock
5 mg	$297	In Stock
10 mg	$529	In Stock
25 mg	$986	In Stock
50 mg	$1,330	In Stock
100 mg	$1,790	In Stock
1 mL x 10 mM (in DMSO)	$336	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.92%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	BLU-222 is an orally available but selective cell cycle protein-dependent kinase (CDK2) inhibitor with antitumor activity for the study of ovarian and uterine cancer.
Synonyms	BLU222, BLU 222

Chemical Properties

Molecular Weight	365.34
Formula	C₁₅H₁₇F₂N₇O₂
Cas No.	2888704-84-3
Smiles	FC(F)OC1=CC(=NN1)NC2=NC3=C(N=C2)C=NN3CC4CCOCC4
Relative Density.	1.67 g/cm3 at 20℃ (Predicted)
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (218.97 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7372 mL	13.6859 mL	27.3718 mL	136.8588 mL
5 mM	0.5474 mL	2.7372 mL	5.4744 mL	27.3718 mL
10 mM	0.2737 mL	1.3686 mL	2.7372 mL	13.6859 mL
20 mM	0.1369 mL	0.6843 mL	1.3686 mL	6.8429 mL
50 mM	0.0547 mL	0.2737 mL	0.5474 mL	2.7372 mL
100 mM	0.0274 mL	0.1369 mL	0.2737 mL	1.3686 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc