Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

Deferitrin

Copy Product Info
🥰Excellent
Catalog No. T19692Cas No. 239101-33-8
Alias GT-56-252, GT-56252, GT 56252, GT 56 252

Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.

Deferitrin

Deferitrin

Copy Product Info
🥰Excellent
Purity: 98.71%
Catalog No. T19692Alias GT-56-252, GT-56252, GT 56252, GT 56 252Cas No. 239101-33-8
Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$106In StockIn Stock
5 mg$247In StockIn Stock
10 mg$383In StockIn Stock
25 mg$612In StockIn Stock
50 mg$859In StockIn Stock
100 mg$1,180In StockIn Stock
1 mL x 10 mM (in DMSO)$228In StockIn Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:98.71%
Appearance:Solid
Color:White
Contact us for more batch information

Resource Download

Product Introduction

Deferitrin AI Summary
Deferitrin exhibits notable bioactivity related to iron-clearing efficiency across various animal models, including Sprague-Dawley rats and Cebus apella primates. Its effectiveness varies by species and dosage, with a higher efficiency observed in iron-loaded Cebus apella at 150 umol/kg (13.4%) compared to other models. In non-iron-overloaded conditions, iron-clearing efficiency ranges from 0.5% to 17.7% depending on specific assay conditions. Deferitrin also demonstrates significant tissue distribution, being present in organs such as the liver, kidney, heart, pancreas, and plasma of rats. In terms of lipophilicity, the compound has a partition coefficient (logP) value of -1.05, indicating slightly negative lipophilicity. Additionally, the compound shows varying iron excretion levels in bile (up to 93.0%), urine (up to 7.0%), and feces, with higher excretion efficiency generally observed in bile. Despite its iron-clearing capabilities, the compound has limited inhibitory activity against murine L1210 cell growth and low intracellular concentration post-treatment..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.
SynonymsGT-56-252, GT-56252, GT 56252, GT 56 252
Chemical Properties
Molecular Weight253.27
FormulaC11H11NO4S
Cas No.239101-33-8
SmilesO=C([C@]1(C)N=C(C2=CC=C(O)C=C2O)SC1)O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (217.16 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.9484 mL19.7418 mL39.4836 mL197.4178 mL
5 mM0.7897 mL3.9484 mL7.8967 mL39.4836 mL
10 mM0.3948 mL1.9742 mL3.9484 mL19.7418 mL
20 mM0.1974 mL0.9871 mL1.9742 mL9.8709 mL
50 mM0.0790 mL0.3948 mL0.7897 mL3.9484 mL
100 mM0.0395 mL0.1974 mL0.3948 mL1.9742 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Deferitrin | purchase Deferitrin | Deferitrin cost | order Deferitrin | Deferitrin chemical structure | Deferitrin formula | Deferitrin molecular weight