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6-AZATHYMINE

Name: 6-AZATHYMINE
Brand: TargetMol
SKU: T8648
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T8648Cas No. 932-53-6

6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase. 6-Azauracil acted as a competitive inhibitor with respect to beta-alanine, and was an uncompetitive inhibitor with respect to pyruvic acid with a Ki of approximately 8.9 mM.

6-AZATHYMINE

🥰Excellent

Purity: 99.47%

Catalog No. T8648Cas No. 932-53-6

Pack Size	Price	Availability	Quantity
100 mg	$29	In Stock
1 mL x 10 mM (in DMSO)	$39	In Stock

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Batch Information

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Purity:99.47%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase. 6-Azauracil acted as a competitive inhibitor with respect to beta-alanine, and was an uncompetitive inhibitor with respect to pyruvic acid with a Ki of approximately 8.9 mM.
Targets&IC50	Pyruvic acid:8.9 mM

Chemical Properties

Molecular Weight	127.1
Formula	C₄H₅N₃O₂
Cas No.	932-53-6
Smiles	Cc1n[nH]c(=O)[nH]c1=O
Relative Density.	1.67g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 27.5 mg/mL (216.37 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	7.8678 mL	39.3391 mL	78.6782 mL	393.3910 mL
5 mM	1.5736 mL	7.8678 mL	15.7356 mL	78.6782 mL
10 mM	0.7868 mL	3.9339 mL	7.8678 mL	39.3391 mL
20 mM	0.3934 mL	1.9670 mL	3.9339 mL	19.6696 mL
50 mM	0.1574 mL	0.7868 mL	1.5736 mL	7.8678 mL
100 mM	0.0787 mL	0.3934 mL	0.7868 mL	3.9339 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc