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6-AZATHYMINE

🥰Excellent
Catalog No. T8648Cas No. 932-53-6

6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase. 6-Azauracil acted as a competitive inhibitor with respect to beta-alanine, and was an uncompetitive inhibitor with respect to pyruvic acid with a Ki of approximately 8.9 mM.

6-AZATHYMINE

6-AZATHYMINE

🥰Excellent
Purity: 99.47%
Catalog No. T8648Cas No. 932-53-6
6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase. 6-Azauracil acted as a competitive inhibitor with respect to beta-alanine, and was an uncompetitive inhibitor with respect to pyruvic acid with a Ki of approximately 8.9 mM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 mg$29In StockIn Stock
1 mL x 10 mM (in DMSO)$39In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.47%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase. 6-Azauracil acted as a competitive inhibitor with respect to beta-alanine, and was an uncompetitive inhibitor with respect to pyruvic acid with a Ki of approximately 8.9 mM.
Targets&IC50
Pyruvic acid:8.9 mM
Chemical Properties
Molecular Weight127.1
FormulaC4H5N3O2
Cas No.932-53-6
SmilesCc1n[nH]c(=O)[nH]c1=O
Relative Density.1.67g/cm3
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 27.5 mg/mL (216.37 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM7.8678 mL39.3391 mL78.6782 mL393.3910 mL
5 mM1.5736 mL7.8678 mL15.7356 mL78.6782 mL
10 mM0.7868 mL3.9339 mL7.8678 mL39.3391 mL
20 mM0.3934 mL1.9670 mL3.9339 mL19.6696 mL
50 mM0.1574 mL0.7868 mL1.5736 mL7.8678 mL
100 mM0.0787 mL0.3934 mL0.7868 mL3.9339 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

thymineRNASynthesisRNA SynthesisNucleosideAntimetaboliteNucleoside Antimetabolite/AnalogNucleoside AntimetabolitenucleobaseInhibitorinhibitInfluenzaVirusInfluenza VirusDNASynthesisDNA/RNA SynthesisDNA SynthesisDNABacterialantiviralantibacterialAnalogaminotransferase6-nitrogen6-AZATHYMINE6-Azathymine6AZATHYMINE6 AZATHYMINE
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