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Tuberculosis inhibitor 3

Name: Tuberculosis inhibitor 3
Brand: TargetMol
SKU: T38298
Price: 71 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T38298Cas No. 2219325-28-5

Tuberculosis inhibitor 3 (compound 2i) is a highly potent and orally bioavailable anti-tuberculosis drug with in vitro antidrug activity of MIC < 0.016 μg/mL against both drug-sensitive and drug-resistant Mycobacterium tuberculosis, H37RV & MDR-TB.

Tuberculosis inhibitor 3

🥰Excellent

Purity: 98.8%

Catalog No. T38298Cas No. 2219325-28-5

Pack Size	Price	Availability
1 mg	$71	In Stock
5 mg	$172	In Stock
10 mg	$277	In Stock
25 mg	$565	In Stock
50 mg	$813	In Stock
100 mg	$1,190	In Stock
1 mL x 10 mM (in DMSO)	$198	In Stock

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Purity:98.8%

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COA LCMS HNMR

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Tuberculosis inhibitor 3 (compound 2i) is a highly potent and orally bioavailable anti-tuberculosis drug with in vitro antidrug activity of MIC < 0.016 μg/mL against both drug-sensitive and drug-resistant Mycobacterium tuberculosis, H37RV & MDR-TB.
In vitro	Tuberculosis inhibitor 3 (Compound 2i) were found to display potent anti-TB activity (MIC < 0.016 µg/mL) against drug-sensitive/resistant MTB strains[1].

Chemical Properties

Molecular Weight	524.48
Formula	C₂₁H₂₂F₆N₄O₃S
Cas No.	2219325-28-5
Smiles	O=C1N=C(SC2=C1C=C(C=C2N(=O)=O)C(F)(F)F)N3CCC(CN4CCC(CC4)C(F)(F)F)CC3
Relative Density.	1.60 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 20 mg/mL (38.13 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9067 mL	9.5333 mL	19.0665 mL	95.3325 mL
5 mM	0.3813 mL	1.9067 mL	3.8133 mL	19.0665 mL
10 mM	0.1907 mL	0.9533 mL	1.9067 mL	9.5333 mL
20 mM	0.0953 mL	0.4767 mL	0.9533 mL	4.7666 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc