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BRAF inhibitor

Name: BRAF inhibitor
Brand: TargetMol
SKU: T10599
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T10599Cas No. 918505-61-0

BRAF inhibitor is an inhibitor of B-Raf.

BRAF inhibitor

🥰Excellent

Purity: 98.41%

Catalog No. T10599Cas No. 918505-61-0

BRAF inhibitor is an inhibitor of B-Raf.

Pack Size	Price	Availability
1 mg	$39	In Stock
5 mg	$94	In Stock
10 mg	$147	In Stock
25 mg	$263	In Stock
50 mg	$413	In Stock
100 mg	$589	In Stock
200 mg	$855	In Stock
1 mL x 10 mM (in DMSO)	$106	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:98.41%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

BRAF inhibitor is an inhibitor of B-Raf.

Chemical Properties

Molecular Weight	456.47
Formula	C₂₂H₁₈F₂N₄O₃S
Cas No.	918505-61-0
Smiles	CC(C)S(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(cc23)-c2cccnc2)c1F
Relative Density.	1.45

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 75 mg/mL (164.3 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1907 mL	10.9536 mL	21.9072 mL	109.5362 mL
5 mM	0.4381 mL	2.1907 mL	4.3814 mL	21.9072 mL
10 mM	0.2191 mL	1.0954 mL	2.1907 mL	10.9536 mL
20 mM	0.1095 mL	0.5477 mL	1.0954 mL	5.4768 mL
50 mM	0.0438 mL	0.2191 mL	0.4381 mL	2.1907 mL
100 mM	0.0219 mL	0.1095 mL	0.2191 mL	1.0954 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc