Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Aclimostat (ZGN-1061) is a highly potent inhibitor of the MetAP2 enzyme that demonstrates promising efficacy and safety profiles in preclinical trials. In a mouse model of obesity and insulin resistance, ZGN-1061 exhibits comparable weight loss efficacy to beloranib, while also improving metabolic parameters. Additionally, ZGN-1061 induces consistent changes in gene transcription in HepG2 cells, further supporting its positive pharmacological effects.
Pack Size | Availability | Price/USD | Quantity |
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5 mg | Inquiry | $ 941.00 |
Description | Aclimostat (ZGN-1061) is a highly potent inhibitor of the MetAP2 enzyme that demonstrates promising efficacy and safety profiles in preclinical trials. In a mouse model of obesity and insulin resistance, ZGN-1061 exhibits comparable weight loss efficacy to beloranib, while also improving metabolic parameters. Additionally, ZGN-1061 induces consistent changes in gene transcription in HepG2 cells, further supporting its positive pharmacological effects. |
Synonyms | ZGN-1061, Aclimostat |
Molecular Weight | 478.63 |
Formula | C26H42N2O6 |
CAS No. | 2082752-83-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Aclimostat 2082752-83-6 ZGN-1061 ZGN 1061 ZGN1061 inhibitor inhibit