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Adenine hydrochloride

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Catalog No. T6225Cas No. 2922-28-3
Alias Adenine HCl, 6-Aminopurine hydrochloride

Adenine hydrochloride is a purine nucleobase and a chemical component of DNA and RNA. It is involved in cellular respiration, protein synthesis, and plays an important role in energy metabolism through high-energy molecules such as ATP, NAD, and FAD. It can be used to induce hyperuricemia and chronic kidney injury models.

Adenine hydrochloride

Adenine hydrochloride

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Purity: 98.86%
Catalog No. T6225Alias Adenine HCl, 6-Aminopurine hydrochlorideCas No. 2922-28-3
Adenine hydrochloride is a purine nucleobase and a chemical component of DNA and RNA. It is involved in cellular respiration, protein synthesis, and plays an important role in energy metabolism through high-energy molecules such as ATP, NAD, and FAD. It can be used to induce hyperuricemia and chronic kidney injury models.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 g$30-In Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.86%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Adenine hydrochloride is a purine nucleobase and a chemical component of DNA and RNA. It is involved in cellular respiration, protein synthesis, and plays an important role in energy metabolism through high-energy molecules such as ATP, NAD, and FAD. It can be used to induce hyperuricemia and chronic kidney injury models.
In vivo
Trelagliptin improves glycaemic control by inhibition of DPP-4 activity. [1]
SynonymsAdenine HCl, 6-Aminopurine hydrochloride
Chemical Properties
Molecular Weight171.59
FormulaC5H5N5·HCl
Cas No.2922-28-3
SmilesCl.Nc1ncnc2nc[nH]c12
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 1.72 mg/mL (10.02 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.8278 mL29.1392 mL58.2785 mL291.3923 mL
5 mM1.1656 mL5.8278 mL11.6557 mL58.2785 mL
10 mM0.5828 mL2.9139 mL5.8278 mL29.1392 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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