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FLT3/ITD-IN-4 (Compound 16) is a selective inhibitor of FLT3 internal tandem repeat mutations (FLT3-ITD) with an IC50 of 2.3 nM and is applicable for studying acute myeloid leukemia.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 8-10 weeks | |
50 mg | $1,980 | 8-10 weeks | |
100 mg | $2,500 | 8-10 weeks |
Description | FLT3/ITD-IN-4 (Compound 16) is a selective inhibitor of FLT3 internal tandem repeat mutations (FLT3-ITD) with an IC50 of 2.3 nM and is applicable for studying acute myeloid leukemia. |
Targets&IC50 | FLT3:443 nM (EC50), FLT3 (D835Y):4.84 nM, EphA7:3255 nM (EC50), ZAK/MLTK:1069 nM (EC50), DDR2:2494 nM (EC50), CDK16-CyclinY:1768 nM (EC50), FLT3 (ITD):2.3 nM, RET:277 nM (EC50), MAP4K4:5737 nM (EC50), NTRK1:3857 nM (EC50) |
Molecular Weight | 458.47 |
Formula | C25H22N4O5 |
Cas No. | 2278278-04-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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