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ZINC00881524

Name: ZINC00881524
Brand: TargetMol
SKU: T4095
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T4095Cas No. 557782-81-7

Alias ROCK inhibitor

ZINC00881524 (ROCK inhibitor) is an effective and specific ROCK inhibitor.

ZINC00881524

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Purity: 99.48%

Catalog No. T4095Alias ROCK inhibitorCas No. 557782-81-7

ZINC00881524 (ROCK inhibitor) is an effective and specific ROCK inhibitor.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$54	In Stock	In Stock
50 mg	$83	In Stock	In Stock
100 mg	$127	In Stock	In Stock
200 mg	$187	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.48%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	ZINC00881524 (ROCK inhibitor) is an effective and specific ROCK inhibitor.
Synonyms	ROCK inhibitor

Chemical Properties

Molecular Weight	380.46
Formula	C₂₁H₂₀N₂O₃S
Cas No.	557782-81-7
Smiles	COc1ccc(CC(=O)Nc2nc-3c(CCc4ccccc-34)s2)cc1OC
Relative Density.	1.309 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (157.7 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6284 mL	13.1420 mL	26.2840 mL	131.4199 mL
5 mM	0.5257 mL	2.6284 mL	5.2568 mL	26.2840 mL
10 mM	0.2628 mL	1.3142 mL	2.6284 mL	13.1420 mL
20 mM	0.1314 mL	0.6571 mL	1.3142 mL	6.5710 mL
50 mM	0.0526 mL	0.2628 mL	0.5257 mL	2.6284 mL
100 mM	0.0263 mL	0.1314 mL	0.2628 mL	1.3142 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc